Ligand-Induced Cell Adhesion in Synapse Formation

FERNANDA LEDDA

Cell Interaction

INTECH

Año: 2012; p. 123 - 138

Neuronal Synapses can be considered as a specialized type of cell-cell interactions that mediates communication between neurons and their target cells. It involves the interaction between two asymmetric partners, the presynaptic specialization and the postsynaptic density. Trans-synaptic cell adhesion molecules are particularly attractive candidate mediators of synapse formation because of their potential to bidirectionally coordinate functional and morphological synapse differentiation.