IBCN   20355
INSTITUTO DE BIOLOGIA CELULAR Y NEUROCIENCIA "PROFESOR EDUARDO DE ROBERTIS"
Unidad Ejecutora - UE
artículos
Título:
ApoE epsilon4 is not associated with posictal confusion in patients with mesial temporal lobe epilepsy with hippocampal sclerosis
Autor/es:
KAUFFMAN MARCELO; PEREIRA DE SILVA NAHUEL; CONSALVO DAMIAN; KOCHEN SILVIA
Revista:
EPILEPSY RESEARCH
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Año: 2009 vol. 85 p. 311 - 313
ISSN:
0920-1211
Resumen:
A previous report found an association between ApoE isoforms and postictal
confusion in medically intractable temporal lobe epilepsy (TLE). We performed a molecular
epidemiology study in an independent sample of 77 TLE patients. We failed to replicate the
original allelic association between ApoE 4 allele and postictal confusion in our population
(2 = 1.67; d.f. = 1; p = 0.2). Thus, the association between ApoE 4 allele and postictal confusion
still needs to be fully investigated in different and independent populations.
© 2009 Elsevier B.V. All rights reserved.