INLAIN   20354
INSTITUTO DE LACTOLOGIA INDUSTRIAL
Unidad Ejecutora - UE
capítulos de libros
Título:
Bacteriophage. Biological Aspects
Autor/es:
QUIBERONI, A.; SUÁREZ, V.; BINETTI, A.; REINHEIMER, J.
Libro:
ENCYCLOPEDIA OF DAIRY SCIENCE
Editorial:
Elsevier Limited
Referencias:
Lugar: Kidlington, Oxford; Año: 2011; p. 430 - 438
Resumen:
The inhibitory effect of bacteriophage against lactic acid starters is still recognized as one of the major and persistent troubles in dairy fermentations. This article covers various aspects of these viruses, as a way of updating knowledge of and improving the methodologies of defense against bacteriophage to be used in dairy industry.This article reviews the basic biological aspects of the bacteriophage life cycle. The most recent classification of viruses according to the International Committee on Taxonomy of Viruses (ICTV) and, in particular, the classification of phages of lactic acid bacteria is also discussed. In addition, native phage resistance mechanisms are described (inhibition of phage adsorption, blocking of DNA injection, restriction/modification systems, and abortive infection), including CRISPRs (clustered regularly interspaced short palindromic repeats), the latest defense mechanism revealed in prokaryotes. A summary of engineered phage resistance mechanisms is also presented. Finally, different methodologies to detect bacteriophages in dairy plants are discussed.