Solid state Nuclear Magnetic Resonance: Pharmaceutical Applications

A.K. CHATTAH

Córdoba

Workshop; BRUKER Solid State NMR Workshop; 2009

Compañía BRUKER, FaMAF-UNC

PRESENTACIÓN ORAL DE A.K. CHATTAHSSNMR: Pharmaceutical Applications1) Role, objectives and motivation of solid state technology.2) Introduction to SSNMR of pharmaceutical compounds.3) Pulse sequences most commonly used in our work.4) New pharmaceutical compounds studied in our laboratory: a) Zwitterionic character of procaine and procainamide derivatives.b) Characterization of the aluminium complexes of norfloxacin and ciprofloxacin fluoroquinolonesc)Characterization of Fluoroquinolones-saccharinatesd)Identification of polymorphs and investigation of 1H interactions in the ciprofloxacin saccharinate