High-resolution spectra in PHIP

R.H. ACOSTA; I. PRINA; L. BULJUBASICH

New developments in NMR no. 6. Gas Phase NMR

Royal Society of Chemistry

Año: 2016; p. 304 - 335

Nuclear Magnetic Resonance (NMR) is one of the most powerful analyticaltechniques used for materials characterization at a microscopic level. Theapplication of NMR in science and technology includes chemistry, biology,food research and quality control, environmental studies of plants and soils.Determination of pore structures has a great impact in the oil industry andmedicine. Additionally Magnetic Resonance Imaging (MRI) is perhaps themost powerful diagnosis technique used in medicine in modern days.Despite all the power of NMR, there is a major drawback in its applicationthat is the poor inherent sensitivity of the signals that can be detected. Thisfundamental insensitivity originates from the minuscule size of nuclearmagnetic moments, which results in an exceedingly small equilibrium nuclearspin polarization even in high magnetic fields. Traditionally, NMR hasdealt with excitation and detection of nuclear spin angular momentum insystems in thermal equilibrium with an external static magnetic field. Theintensity of the NMR signal is proportional to the population difference ofquantum states, which is driven by the difference in energy levels and isgiven by gB0/kBT, where g is the nuclear gyromagnetic ratio, B0 is the external