IFEG   20353
INSTITUTO DE FISICA ENRIQUE GAVIOLA
Unidad Ejecutora - UE
artículos
Título:
Latin American Society for Pediatric Research (LASPR) Selected Abstracts from the LIV Annual Meeting
Autor/es:
MARTINEZ JORGE IVAN; DIPIERRI JOSE EDGARDO; ALFARO EMMA LAURA; GRANDI, CARLOS
Revista:
PEDIATRIC RESEARCH
Editorial:
INT PEDIATRIC RESEARCH FOUNDATION, INC
Referencias:
Año: 2017 vol. 81 p. 681 - 684
ISSN:
0031-3998
Resumen:
Background: The increased rate since mid-2015 of microcephaly cases associated with Zika virusin Brazil has determined that WHO declares that this epidemic is an international public healthemergency (PHEIC). An emerging problem is the anthropometric diagnosis of microcephaly. Itrequires deeper knowledge about the cutoffs and references and / or standards to measure the headcircumference (HC) and diagnose suspected cases of microcephaly.Objective: the aim of this study was to compare the distribution of HC by sex and gestational age(GA) of the newborn population of the province of Jujuy, Argentina, with the recently introducedinto clinical practice Intergrowth-21st standards.Methods: The data source was the Perinatal Informatics System (SIP, PHAO/WHO) in the provinceof Jujuy (2008?2013). Inclusion criteria were GA between 24 and 42 weeks and birth weight morethan 500 grams. Exclusion criteria were major and minor malformations, toxoplasmosis and stillbirth.The mean and SD of HC was calculated by gestational age and sex. The differences with theIntergrowth-21st standard were calculated with the Student t test.Results: The sample was constituted by 46,146 newborns (22,799 girls and 23,347 boys). Newbornsfrom Jujuy presented in both sexes a higher HC compared with the Intergrowth-21st standard onall GA, with statistically significant differences in almost all except 24th, 25th, 27th, 28th and 29thweeks in girls and in the 25th week in boys, attributable to small sample size.Conclusion: The application of Intergrowth-21st standard to Jujuy population may overestimatethe suspected cases of microcephaly. New epidemiological studies to assess the specificity and sensitivityof other selection criteria, standards and / or references applicable to the detection of suspectedcases of microcephaly are required, such as the recently published recommendations of theWHO (WHO / ZIKV / MOC / 16.3 / Rev3).