IIIE   20352
INSTITUTO DE INVESTIGACIONES EN INGENIERIA ELECTRICA "ALFREDO DESAGES"
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Mild Alzheimer's disease: evidences from the analysis of eye movement during reading
Autor/es:
FERNÁNDEZ GERARDO ABEL; OROZCO DAVID; CASTRO LILIANA; SCHUMACHER MARCELA; AGAMENNONI OSVALDO
Lugar:
Viena
Reunión:
Conferencia; ECEM; 2015
Institución organizadora:
Universidad de Viena
Resumen:
We analyzed the eye movement behavior of thirty five healthy readers (Controls) and thirtyfive patients with probable Alzheimer disease (AD) during reading Spanish regular andhighly-predictable sentences. We used lineal mixed models to analyze eye movement information.The cloze predictability of words N-2, N-1, and N+1 exerted an influence onreader?s gaze duration. The predictabilities of preceding words in highly-predictable sentencesserved as task-appropriate cues that were used by Controls readers. In contrast, theseeffects were not present in AD patients. For analyzing retrieval memory we determined, foreach sentence, a word at which predictability of words grows significantly. In Controls,changes in predictability significantly affected fixation duration along the sentence; noteworthy,these changes did not affect fixation durations in AD patients. Our results suggestthat Controls used stored information of familiar texts for enhancing their reading performanceand imply that contextual-word predictability, whose processing require memoryretrieval, only affected reading behavior in healthy subjects. In AD, this loss might revealimpairments in brain areas such as those corresponding to working memory and memoryretrieval. These findings might be relevant for expanding the options for the early detectionand monitoring in the early stages of AD.