Effect of Lacobacillus reuteri on the Prevention of Hypercholesterolemia in Mice

TARANTO, MARIA PIA; MEDICI, MARTA; PERDIGON, GABRIELA; RUIZ HOLGADO, AIDA; FONT DE VALDEZ, GRACIELA

JOURNAL OF DAIRY SCIENCE

American Dairy Science Association

Lugar: USA; Año: 2000 vol. 83 p. 401 - 403

0022-0302

Administration of Lactobacillus reuteri CRL 1098 (104 cells/d) to mice for 7 d before inducing hypercholesterolemia (by feeding mice with a fat-enriched diet for the subsequent 7 d) was evaluated. At this low dose, L. reuteriLactobacillus reuteri CRL 1098 (104 cells/d) to mice for 7 d before inducing hypercholesterolemia (by feeding mice with a fat-enriched diet for the subsequent 7 d) was evaluated. At this low dose, L. reuteriL. reuteri was effective in preventing hypercholesterolemia in mice, producing a 17% increase in the ratio of highdensity lipoprotein to low-density lipoprotein. Total cholesterol  and triglycerides decreased by 22 and 33%, respectively, in the group that was not fed the lactobacilli. The hypocholesterolemic effect produced by L. reuteriL. reuteri CRL 1098 might be considered as indirect evidence of the permanency of the lactobacilli in the gut