INVESTIGADORES
GLEISER Raquel Miranda
artículos
Título:
Synthesis, structural elucidation and larvicidal activity of novel arylhydrazones
Autor/es:
P, NEFISATH; DASAPPA, JAGADEESH PRASAD; B, HARIPRIYA; CHOPRA, DEEPAK; VENUGOPALA, KATHARIGATTA N.; DEB, PRAN KISHORE; GLEISER, RAQUEL M.; MOHANLALL, VIRESH; MAHARAJ, RAJENDRA; SHASHIPRABHA, NULL; POOJARY, VISHWANATHA
Revista:
JOURNAL OF MOLECULAR STRUCTURE
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Año: 2021 vol. 1236
ISSN:
0022-2860
Resumen:
The present study focuses on a series of novel hydrazones of 2- [3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carbohydrazide (5a-l) for their larvicidal activity against Anopheles arabiensis. The synthesis of the title compounds was achieved by the conventional reflux method, and structures of the novel compounds were ascertained by FT-IR, NMR (1H &13C), LC-MS, and elemental analysis. Compound (5l) was studied by single crystal X-ray diffraction for intra and intermolecular interactions. Title compounds (E)-2-(3-cyano-4-isobutoxyphenyl)-N´-(4-fluoro-3-phenoxybenzylidene)-4-methylthiazole-5-carbohydrazide (5a) and (E)-N´-(4-Chlorobenzylidene)-2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carbohydrazide (5g) emerged as promising larvicidal agents against Anopheles arabiensis.