FLORENCIA GONZÁLEZ LIZÁRRAGA; CESAR LUIS AVILA; DIEGO PLOPER; BENJAMÍN SOCIAS; RODRIGO TOMAS-GRAU; SABRINA SEQUEIRA; ROSA MELLA; PATRICIA VILLACÉ LOZANO; PATRICK MICHEL; CLARISA SALADO; RITA RAISMAN-VOZARI; ROSANA CHEHÍN

PICTA: NOVEL CELLULAR PLATFORM FOR MONITORING PARKINSON´S DISEASE-RELATED EVENTS

SLAS2023 International Conference and Exhibition

Año: 2023;

DIEGO PLOPER; AGUSTÍN O. PERNICONE; VERONICA MANZANO; BENJAMÍN SOCIAS; CESAR LUIS AVILA; ESTEBAN VERA PINGITORE; ANALIA SILVINA CHAVES; ADRIANA A. KOLENDER; RODRIGO TOMAS-GRAU; FLORENCIA GONZALEZ LIZARRAGA; MARTIN LUOUNG; OSCAR VARELA; CHEHÍN ROSANA

A NOVEL DOPAMINE AGONIST WITH NEUROPROTECTIVE EFFECT

Federation of European Neuroscience Societies (FENS)

Lugar: Paris; Año: 2022;

RODRIGO TOMAS-GRAU; FLORENCIA GONZALEZ LIZARRAGA; DIEGO PLOPER; CESAR LUIS AVILA; SERGIO B. SOCÍAS; PIERRE BESNAULT; AURORE TOURVILLE; ROSA MELLA; PATRICIA VILLACÉ LOZANO; CLARISA SALADO; JEAN MICHEL BRUNEL; LAURENT FERRIÉ; RITA RAISMAN-VOZARI; PATRICK MICHEL; BRUNO FIGADÉRE; ROSANA CHEHÍN

Neuroprotective effects of a novel demeclocycline derivative lacking antibiotic activity: from a hit to a promising lead compound

Federation of European Neuroscience Societies (FENS)

Lugar: Paris; Año: 2022;

FLORENCIA GONZALEZ LIZARRAGA; CESAR LUIS AVILA; DIEGO PLOPER; SERGIO B. SOCÍAS; RODRIGO TOMAS-GRAU; SABRINA SEQUEIRA; PATRICK MICHEL; ROSA M. MELLA; PATRICIA VILLACÉ LOZANO; CLARISA SALADO; ROSANA CHEHÍN; RITA RAISMAN-VOZARI

A NEW CELLULAR MODEL TO STUDY ALPHA-SYNUCLEIN AGGREGATION, SEEDING AND PHOSPORILATION

International Conference on Alzheimer' and Parkinson's Diseases and related neurological disorders

Lugar: Barcelona; Año: 2022;

RITA RAISMAN-VOZARI; FLORENCIA GONZALEZ LIZARRAGA; DIEGO PLOPER; CESAR LUIS AVILA; SERGIO SOCÍAS; MAURICIO DOS-SANTOS-PEREIRA; BELÉN MACHÍN; ELAINE DEL-BEL; PATRICK MICHEL; LÍA ISABEL PIETRASANTA; ROSANA CHEHÍN

The non-antibiotic tetracycline CMT-3 inhibits a-synuclein aggregation, seeding and neuroinflammation

Virtual Forum of Neuroscience (FENS)

Año: 2020;

RITA RAISMAN-VOZARI; FLORENCIA GONZALEZ LIZARRAGA; DIEGO PLOPER; BENJAMÍN SOCIAS; CESAR LUIS AVILA; PATRICK MICHEL; ROSANA CHEHÍN

Incyclinide, a non-antibiotic tetracycline, prevents alpha-synuclein aggregation and disrupts fibrillary forms of the protein

Society for Neurosciencie 2019

Lugar: Chicago; Año: 2019;

FLORENCIA GONZÁLEZ LIZÁRRAGA; CESAR LUIS AVILA; DIEGO PLOPER; SERGIO B. SOCÍAS; PATRICK MICHEL; RITA RAISMAN-VOZARI; LÍA ISABEL PIETRASANTA ; ROSANA CHEHÍN

Anti-aggregation and disaggregation properties of the non-antibiotic tetracycline Incyclinide against the Parkinson disease protein alpha-synuclein

Revisiting the Central Dogma of Molecular Biology at the Single-Molecule Level

Lugar: Lima; Año: 2019;

FLORENCIA GONZALEZ LIZARRAGA; SERGIO SOCÍAS; CÉSAR ÁVILA; DIEGO PLOPER; NOUR FRANCIS; LIA PIETRASANTA; RITA RAISMAN-VOZARI; ROSANA CHEHÍN

CHEMICALLY MODIFIED TETRACYCLINE (CMT) INHIBITS ALPHA-SYNUCLEIN AMYLOID FIBERS FORMATION AND NEUROINFLAMMATION

Society for Neuroscience 2018

Lugar: San Diego; Año: 2018;

MEDINA, L.; SEQUEIRA, S.; VERA, C.; GONZALEZ LIZARRAGA, F; BARBOSA, L.; PAPY-GARCIA, D; RAISMAN- VOZARI, R; CHEHÍN, R.

Doxycycline interacts with tau forming different oligomeric species: expanding the target for pautative repurposing of this drug

11th FENS Forum of Neuroscience

Año: 2018;

P. P. MICHEL; M. DOS-SANTOS PEREIRA; L. ACUÑA; S. HAMADAT; J. ROCCA; F. GONZÁLEZ LIZARRAGA; R. N. CHEHÍN; J. SEPULVEDA-DIAZ; E. DEL BEL; R. RAISMAN VOZARI

The neurotransmitter dopamine inhibits glutamate release evoked by α-Synuclein aggregates in microglial cells.

Glia Meeting

Año: 2017;

RITA RAISMAN-VOZARI; LEONARDO ACUÑA; SABAH HAMADAT; NATALIA CORBALÁN; GONZÁLEZ LIZÁRRAGA, F.; JEREMY ROCCA; DULCE PAPY- GARCIA; PATRICK MICHEL; ROSANA CHEHÍN; JULIA SEPÚLVEDA

RIFAMPICIN SUPPRESSES ALPHA-SYNUCLEIN INDUCED MICROGLIAL ACTIVATION AND IMPROVE NEURON SURVIVAL AGAINST INFLAMMATION

Glia Meeting

Año: 2017;

FLORENCIA GONZÁLEZ LIZÁRRAGA; SERGIO B. SOCÍAS; CÉSAR L. ÁVILA; CLARISA M. TORRES-BUGEAU; LEANDRO R. S. BARBOSA; ANDRES BINOLFI; ROSANGELA ITRI; JULIA SEPULVEDA-DIAZ; DULCE PAPY- GARCIA ; ROSANA N. CHEHÍN; RITA RAISMAN-VOZARI

New therapeutic perspective for Parkinsons disease: Doxycycline inhibits the formation of α-synuclein toxic species

10 th FENS Forum of Neuroscience

Año: 2016;

FLORENCIA GONZALEZ LIZARRAGA; BENJAMÍN SOCIAS; CESAR LUIS AVILA; CLARISA M. TORRES-BUGEAU; LEANDRO BARBOSA; ANDRES BINOLFI; CLAUDIO O. FERNANDEZ; DULCE PAPY-GARCIA; JULIA E. SEPÚLVEDA-DÍAZ; RITA RAISMAN-VOZARI; ROSANA CHEHÍN

Repurposing tetracyclines for treatment of Synucleinopathies

2nd Federation of Latinoamerican and Caribbean Neuroscience Societies

Año: 2016;

MEDINA, L.; SEQUEIRA, S.; VERA, CECILIA; GONZALEZ LIZARRAGA, F; RAMOS SOUZA BARBOSA, L; SOCIAS, B; RAISMAN-VOZARI, R; CHEHÍN, RN

Biophysical characterization of tau amyloid aggregation: possible neuroprotective mechanism of doxycycline in tauopathies

2nd Federation of Latinoamerican and Caribbean Neuroscience Societies

Año: 2016;

CHAVES, SM; VERA-PINGUITORE, E; GONZALEZ-LIZARRAGA, MF; CHEHÍN ROSANA

Silicate-induced amyloid nanofibrils for technological applications

XLIV Reunion Anual de la Sociedad Argentina de Biofisica

Año: 2015;

MEDINA, L; VERA, C; RAISMAN-VOZARI R,; PAPY-GARCIA D,; CHEHÍN ROSANA.

Biophysical characterization of tau amyloid aggregationand the intermediates interaction with biological membranes

Latin American Crosstalk in Biophysics and Physiology

Año: 2015;

BALEANI, M; AVILA CL; CHEHÍN ROSANA

Caracterización del espectro de fluorescencia de GAPDH. Aplicación al estudio de agregación proteico

XLIV Reunión Anual SAB 2015

Año: 2015;

BALEANI, M; AVILA CL; PAPY-GARCIA D,; CHEHÍN ROSANA

Design of a molecule capable of inducing the formation of neuroprotective protofibrils of GAPDH

Latin American Crosstalk in Biophysics and Physiology

Lugar: Salto; Año: 2015;

SEPULVEDA-DIAZ J; SOCÍAS, B; TORRES BUGEAU, C.; PAPY-GARCIA D,; MICHEL P; CHEHÍN ROSANA; RAISMAN-VOZARI R,

Modulation of microglal inflammatory response to alpha-synuclein oligomers by heparin-induced GAPDH prefibrils

Neurosciences 2015. 45th Annual Society for Neuroscience Meeting

Lugar: Chicago; Año: 2015;

CHEHÍN ROSANA

Potential application of acid urease immobilization on biological nanotubes

Giornate del CUIA in Argentina

Lugar: Buenos Aires; Año: 2014;

GONZALEZ-LIZARRAGA, MF; CLARISA M. TORRES BUGEAU; SOCÍAS, B; AVILA CL; BARBOSA LR,; ITRI R,; PAPY-GARCIA D,; RAISMAN-VOZARI R,; AVILA CL, TORRES-BUGEAU CM, BARBOSA LR, MORANDÉ SALES E, OUIDJA MO, SOCÍAS SB, CELEJ MS, RAISMAN-VOZARI R, PAPY-GARCIA D, ITRI R, CHEHIN RN; CHEHÍN RN

Doxycycline leads to the formation of off-pathway non toxic alfa-Synuclein oligomers

XLIII Reunion Anual de la Sociedad Argentina de Biofisica

Lugar: Sierra de la Ventana; Año: 2014;

AVILA CL; BARBOSA LR,; ITRI R,; CHEHÍN RN

The combination of SAXS with computational biology techniques can provide insight to understand the neuroprotective effect of GAPDH protofibrils

X Reunion Anual de la Asociación Argentina de Cristalografia

Lugar: Mar del Plata; Año: 2014;

AVILA CL,; CLARISA M. TORRES BUGEAU; VERA C; GONZALEZ-LIZARRAGA, MF; BARBOSA LR,; RAISMAN-VOZARI R,; PAPY-GARCIA D,; ITRI R,; CHEHÍN RN

Structural characterization of GAPDH protofibrils formed in the presence of acidic membranes

XLIII Reunion Anual de la Sociedad Argentina de Biofisica

Lugar: Sierra de la Ventana; Año: 2014;

TORRES BUGEAU, CLARISA; AVILA CL,; GONZALEZ-LIZARRAGA, MF; VERA, C; BARBOSA LR,; ITRI R,; CHEHÍN RN

Structural characterization of membrane-induced GAPDH prefibrillar species and its implications in Parkinson disease

XXIX Reunion Anual FESBE

Lugar: Catxambu; Año: 2014;

AVILA CL; AVILA CL, TORRES-BUGEAU CM, BARBOSA LR, MORANDÉ SALES E, OUIDJA MO, SOCÍAS SB, CELEJ MS, RAISMAN-VOZARI R, PAPY-GARCIA D, ITRI R, CHEHIN RN; BARBOSA LR,; ITRI R,; PAPY-GARCIA D,; CHEHÍN RN

Modelo estructural de protofibrillas de GAPDH capaces de secuestrar alfa-sinucleina

Segundo Workshop de Usuarios Argentinos de Técnicas de Luz Sincrotrón

Lugar: Bariloche; Año: 2013;

AVILA CL,; TORRES BUGEAU, C.; BARBOSA LR,; MORANDÉ SALES, E; OUIDJA, O; SOCÍAS, B; RAISMAN-VOZARI R,; PAPY-GARCIA D,; ITRI R,; CHEHÍN RN

Structural characterization of heparin-induced GAPDH protofibrils preventing alfa- synucleinoligomeric species toxicity

XLII Reunion Anual de la Sociedad Argentina de Biofisica

Lugar: Carlos Paz, Cordoba; Año: 2013;

AVILA CL,; CHEHÍN RN

Molecular dynamic studies of heparin binding to glyceraldehyde-3-phosphate dehydrogenase

IV Congreso Argentino de Bioinformática & IV Conferencia de SOIBIO

Lugar: Rosario; Año: 2013;

TORRES BUGEAU, CLARISA; AVILA, CÉSAR; CHEHIN R

Rol de las membranas biológicas en la agregación amiloide de GAPDH

XL Reunión Anual de la Sociedad Argentina de Biofísica.

Lugar: Buenos Aires; Año: 2011;

TORRES BUGEAU, CLARISA; AVILA, CÉSAR; CHEHÍN ROSANA

Computational prediction of glycosamineglycanes binding to GAPDH and its implication in neurodegenerative disease

X-Meeting

Lugar: Florianópolis; Año: 2011;

TORRES BUGEAU, CLARISA; AVILA, CÉSAR; CHEHÍN ROSANA

Prediction of heparin binding sites on GAPDH

2do Congreso Argentino de Bioinformática y Biología Computacional

Lugar: Córdoba; Año: 2011;

ROSANA CHEHÍN

Protein aggregation and glycosaminoglycans.

2nd European intensive Programo on Proteoglycans and glycosaminoglycans.

Lugar: Paris; Año: 2011;

ROSANA CHEHÍN

“Glyceraldehyde-3-phosphate deshydrogenase early oligomers can alter the alpha-synuclein aggregation kinetics: role of Glycosaminoglycans .

Workshop on Potein Dynamics and Reactivity.

Lugar: Yerba Buena; Año: 2011;

CHEHÍN ROSANA

“Glyceraldehide-3-phosphate dehydrogenase amyloid folding pathway studied by infrared spectroscopy”

3rd Internacional Workshop on Spectroscopy for Biology

Lugar: Marecias (Sao Paolo); Año: 2010;

CLARISA M. TORRES BUGEAU; CESAR AVILA; RAISMAN-VOZARI R,; PAPY-GARCIA D,; LEONARDO M. CORTEZ; ROSANA CHEHÍN

GAPDH: unveiling the seeds of neurodegenerative disease

XXXIX Annual Meeting of the Argentinean Biophysical Society and 3rd Latinoamerican Protein Society Meeting. 12

Lugar: Salta; Año: 2010;

SILVINA CHAVES; CLARISA M. TORRES BUGEAU; CLAUDIO BORSARELLI; CHEHÍN ROSANA

Lysozyme aggregation could expand its spectrum of bactericidal activity

3rd Latin American Protein Society Meeting. XXXIX Annual Meeting of the Argentinean Biophysical Society

Lugar: Salta; Año: 2010;

DUPUY, FERNANDO; AVILA, CÉSAR; TORRES BUGEAU, CLARISA; CHEHÍN, ROSANA; ; MORERO ROBERTO

Microcin J25 membrane interaction: selectivity toward gel phase

XXXVIII Reunión Anual de la Sociedad Argentina de Biofísica.

Lugar: Los Cocos- Córdoba- Argentina; Año: 2009;

TORRES BUGEAU, C.; CORTEZ L; AVILA, C.L; FARÍAS R.N; MORERO, R.D; CHEHÍN R.

Lipid-induced conformational changes in glyceraldehyde-3- phosphate dehydrogenase lead to tetramer dissociation and amyloid fibril formation

XXXVIII Reunión Anual de la Sociedad Argentina de Biofísica.

Lugar: Los Cocos- Córdoba- Argentina; Año: 2009;

CÉSAR L. AVILA; ; BEATRIZ F. DE ARCURI; DANILO GONZALEZ NILO; JAVIER DE LAS RIVAS,; ROBERTO MORERO; ROSANA CHEHÍN

Role of electrostatics on membrane binding, aggregation and destabilization induced by NAD(P)H dehydrogenases. Implication on membrane fusion

Workshop en Biología Computacional de Proteínas

Lugar: Universidad de Quilmes- Argentina; Año: 2009;

CLARISA M. TORRES BUGEAU; FERNANDO DUPUY; CÉSAR L. AVILA; ROBERTO MORERO; ROSANA CHEHÍN

Bilayer conformational changes induced by the antibiotic peptide MccJ25 binding: new insights in its nechanism of action

International Conference and meetings EMBnet-RiBio

Lugar: Riviera Maya- Mexico; Año: 2009;

CHALÓN M.; CORTEZ L.; CHEHÍN R.; FARÍAS R.; VINCENT P

The antibiotic peptide Microcin J25 is a redox peptide

Anual de la Sociedad Argentina de Investigaciones en Bioquímica y Biología Molecular.

Lugar: Carlos Paz- Córdoba; Año: 2008;

AVILA, C.L; MORERO, R.D.; CHEHÍN, R.

Coarse grained molecular dynamics study of the interaction between GAPDHR and small unilamellar vesicles

XXXVII Reunión Anual de la Sociedad Argentina de Biofísica.

Lugar: La Plata- Argentina; Año: 2008;

TORRES BUGEAU, C.; DUPUY, F.; AVILA, C.L.; MORERO, R.D.; CHEHÍN, R

Molecular dynamics and FTIR studies of Microcin J25 and lipid membrana interaction

XXXVII Reunión Anual de la Sociedad Argentina de Biofísica.

Lugar: La Plata- Argentina; Año: 2008;

TORRES BUGEAU, C.; CORTEZ, L.; AVILA, C.L.; MORERO, R.D.; CHEHÍN, R.

Influence of membrana composition on the amyloidogenic properties of glyceraldehide 3P-dehydrogenase

XXXVII Reunión Anual de la Sociedad Argentina de Biofísica.

Lugar: La Plata- Argentina; Año: 2008;

CORTEZ, LM; FARÍAS R.N; CHEHÍN R.

Protective effect of thyroxine, 3,5,3´-triiodothyroacetic acid and 3,5,3´,5´tetraiodothyroacetic acid on serum albumin fibrilation

. XXXVII Reunión Anual de la Sociedad Argentina de Biofísica.

Lugar: La Plata- Argentina; Año: 2008;

AVILA CL; DANILO GONZALEZ NILO; DE LAS RIVAS J; MORERO R; CHEHIN R

Molecular dynamic simulations of the interaction between glyceraldehyde-3-phospate dehydrogenase and lipid bilayers

IV International conference of Biological Physics

Lugar: Montevideo- Uruguay; Año: 2007;

CORTEZ L; FARÍAS R; ´CHEHÍN R

An FTIR approach to the Thyroid Hormones- Membranes Interaction

International Workshop on Infrared Spectroscopy Applied to Biological and Biomimetic Systems: From the Isolated Molecule to the Cell

Lugar: Buenos Aires- Argentina; Año: 2007;

AVILA CL; ARCURI, B.F; GONZALEZ NILO, FD; DE LAS RIVAS J; MORERO, RD; CHEHÍN RN

A novel approach to elucidate the membrane fusion process induced by some soluble redox enzymes, which lack the classical fusion peptide, is presented. Studies on the requirements of several protein dehydrogenases to bind, aggregate and destabilize lipid

Biofisica de macromoléculas: aspectos estructurales e implicancias biológicas y biotecnológicas

Lugar: Quilmes- Argentina; Año: 2007;

CHEHÍN RN

Insights into the mechanism of membrane fusion induced by cytoplasmatic dehydrogenases: role of the positively charged crevices

Internacional Workshop oin Collaborative Bioinformatics- EMBnet-Rib

Lugar: Málaga- España; Año: 2007;

DUPUY, F; CHEHÍN, RN; MORERO, R.D

Evidences of a cooperative partition of the MccJ25 peptide into membranes

. IV International conference of Biological Physics

Lugar: Montevideo- Uruguay; Año: 2007;

DUPUY, F; CHEHÍN, R.; MORERO R

An FTIR molecular view of the interaction between the antibiotic peptide Microcin J25 and membranes

International Workshop on Infrared Spectroscopy Applied to Biological and Biomimetic Systems: From the Isolated Molecule to the Cell

Lugar: Buenos Aires- Argentina; Año: 2007;

AVILA CL; MORERO, R.D; CHEHÍN RN

FTIR studies on the interaction between glyceraldehyde-3-phosphate dehydrogenase and lipid bilayers

International Workshop on Infrared Spectroscopy Applied to Biological and Biomimetic Systems: From the Isolated Molecule to the Cell

Lugar: Buenos Aires- Argentina; Año: 2007;

CÉSAR LUIS AVILA; MORERO, R.D; CHEHÍN RN

Fusión de membranas inducida por enzimas redox: evidencias biofísicas y bioinformáticas de un nuevo mecanismo de acción

Biofisica de macromoléculas: aspectos estructurales e implicancias biológicas y biotecnológicas

Lugar: Quilmes- Argentina; Año: 2007;

CASTELLANO PATRICIA; VIGNOLO GRACIELA; FARÍAS RICARDO; RODRÍGUEZ ARRONDO JOSÉ LUIS; CHEHÍN ROSANA

A molecular view by FTIR spectroscopy of the relationship between the antibiotic peptide lactocin 705 and membranes: speculations on antimicrobial

”. International Workshop on Infrared Spectroscopy Applied to Biological and Biomimetic Systems: From the Isolated Molecule to the Cell

Lugar: Buenos Aires- Argentina; Año: 2007;

ROSANA CHEHÍN

“New insights in membrane fusion: role of surface electrostatic potential

II Jornadas Iberoamericanas de Bioinformática

Lugar: Buenos Aires; Año: 2006;

CÉSAR LUIS AVILA; BEATRIZ FERNÁNDEZ DE ARCURI; DANILO GONZALEZ NILO; ROSANA CHEHÍN; ROBERTO MORERO

Role of surface electrostatic potential on the association of dehydrogenases to model membranas

XXXV Reunión Anual de la Sociedad Argentina de Biofísica

Lugar: Rosario- Argentina; Año: 2006;

CÉSAR LUIS AVILA; BEATRIZ FERNÁNDEZ DE ARCURI; DANILO GONZALEZ NILO; ROSANA CHEHÍN; ROBERTO MORERO

Fenómenos de superficie controlarían la fusión de membranas inducida por proteínas globulares solubles

XXXIV Reunión Anual de la Sociedad Argentina de Biofísica

Lugar: Carlos Paz- Córdoba (Argentina); Año: 2005;

CASTELLANO PATRICIA; VIGNOLO GRACIELA; FARÍAS RICARDO; RODRÍGUEZ ARRONDO JOSÉ LUIS; CHEHÍN ROSANA

Estudios espectroscopicos de Lactocina 705: probable mecanismo de acción

XXXIV Reunión Anual de la Sociedad Argentina de Biofísica

Lugar: Carlos Paz- Córdoba (Argentina); Año: 2005;

ISSE BLANCA; FARIAS RICARDO N.; RODRIGUEZ ARRONDO JOS¡§¦ LUIS; CHEHIN ROSANA

Interaccion de Hormonas Tiroideas con bicapas lipidicas: evidencias de la formaci¡¡ì®n de un nuevo intermediario

XXXIV Reunion Anual de la Sociedad Argentina de Biofisica

Lugar: Carlos Paz- Cordoba (Argentina); Año: 2005;

ROSANA CHEHÍN

Identificación de un nuevo motivo de oxidoreducción de cobre en proteobacterias

I Jornadas Iberoamericanas sobre Bioinformática

Lugar: Cartagena de Indias- Colombia; Año: 2005;