INVESTIGADORES
CHEHIN Rosana Nieves
artículos
DOMINGUEZ-MEIJIDE, ANTONIO; PARRALES, VALERIA; VASILI, EFTYCHIA; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; KÖNIG, ANNEKATRIN; LÁZARO, DIANA F.; LANNUZEL, ANNIE; HAIK, STÉPHANE; DEL BEL, ELAINE; CHEHÍN, ROSANA; RAISMAN-VOZARI, RITA; MICHEL, PATRICK P.; BIZAT, NICOLAS; OUTEIRO, TIAGO FLEMING
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo
NEUROBIOLOGY OF DISEASE; Año: 2021 vol. 151 p. 105256 - 105275
MEDINA, LUCIANA; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; DOMINGUEZ-MEIJIDE, ANTONIO; PLOPER, DIEGO; PARRALES, VALERIA; SEQUEIRA, SABRINA; CIMA-OMORI, MARIA-SOL; ZWECKSTETTER, MARKUS; DEL BEL, ELAINE; MICHEL, PATRICK P.; OUTEIRO, TIAGO FLEMING; RAISMAN-VOZARI, RITA; CHEHÍN, ROSANA; SOCIAS, SERGIO B.
Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity
Frontiers in Aging Neuroscience; Año: 2021 vol. 13
FERREIRA JUNIOR, NILSON CARLOS; DOS SANTOS PEREIRA, MAURÍCIO; FRANCIS, NOUR; RAMIREZ, PAOLA; MARTORELL, PAULA; GONZÁLEZ-LIZARRAGA, FLORENCIA; FIGADÈRE, BRUNO; CHEHIN, ROSANA; DEL BEL, ELAINE; RAISMAN-VOZARI, RITA; MICHEL, PATRICK PIERRE
The chemically-modified tetracycline col-3 and its parent compound doxycycline prevent microglial inflammatory re-sponses by reducing glucose-mediated oxidative stress
Cells; Año: 2021 vol. 10
TOMAS-GRAU, RODRIGO HERNÁN; PLOPER, DIEGO; ÁVILA, CÉSAR LUIS; VERA PINGITORE, ESTEBAN; MALDONADO GALDEANO, CAROLINA; CHAVES, SILVINA; SOCIAS, SERGIO BENJAMÍN; STAGNETTO, AGUSTÍN; NAVARRO, SILVIA ADRIANA; CHAHLA, ROSSANA ELENA; AGUILAR LÓPEZ, MÓNICA; LLAPUR, CONRADO JUAN; AZNAR, PATRICIA; ALCORTA, MARÍA ELENA; COSTAS, DARDO; FLORES, ISOLINA; HEINZE, DAR; APFELBAUM, GABRIELA; MOSTOSLAVSKY, RAUL; MOSTOSLAVSKY, GUSTAVO; CAZORLA, SILVIA INÉS; PERDIGÓN, GABRIELA DEL VALLE; CHEHÍN, ROSANA
Elevated Humoral Immune Response to SARS-CoV-2 at High Altitudes Revealed by an Anti-RBD “In-House” ELISA
Frontiers in Medicine; Lugar: Lausane; Año: 2021 vol. 8
MACHÍN, BELÉN; CHAVES, SILVINA; ÁVILA, CÉSAR; PERA, LICIA MARÍA; CHEHÍN, ROSANA NIEVES; VERA PINGITORE, ESTEBAN
Highly reusable invertase biocatalyst: Biological fibrils functionalized by photocrosslinking
FOOD CHEMISTRY; Año: 2020 vol. 331
GONZÁLEZ-LIZÁRRAGA, FLORENCIA; PLOPER, DIEGO; ÁVILA, CÉSAR L.; SOCÍAS, SERGIO B.; DOS-SANTOS-PEREIRA, MAURICIO; MACHÍN, BELÉN; DEL-BEL, ELAINE; MICHEL, PATRICK PIERRE; PIETRASANTA, LÍA I.; RAISMAN-VOZARI, RITA; CHEHÍN, ROSANA
CMT-3 targets different α-synuclein aggregates mitigating their toxic and inflammogenic effects
Scientific Reports; Año: 2020 vol. 10 p. 1 - 17
ACUÑA, NULL; HAMADAT, NULL; CORBALÁN, NULL; GONZÁLEZ-LIZÁRRAGA, NULL; DOS-SANTOS-PEREIRA, NULL; ROCCA, NULL; DÍAZ, NULL; DEL-BEL, NULL; PAPY-GARCÍA, NULL; CHEHÍN, NULL; MICHEL, NULL; RAISMAN-VOZARI, NULL
Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates
Cells; Lugar: Lucerna; Año: 2019 vol. 8
BORTOLANZA, MARIZA; NASCIMENTO, GLAUCE C.; SOCIAS, SERGIO B.; PLOPER, DIEGO; CHEHÍN, ROSANA N.; RAISMAN-VOZARI, RITA; DEL-BEL, ELAINE
Tetracycline repurposing in neurodegeneration: focus on Parkinson’s disease
JOURNAL OF NEURAL TRANSMISSION. GENERAL SECTION.; Lugar: Viena; Año: 2018
SOCIAS, SERGIO B.; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; AVILA, CESAR L.; VERA, CECILIA; ACUÑA, LEONARDO; SEPULVEDA-DIAZ, JULIA E.; DEL-BEL, ELAINE; RAISMAN-VOZARI, RITA; CHEHIN, ROSANA N.
Exploiting the therapeutic potential of ready-to-use drugs: Repurposing antibiotics against amyloid aggregation in neurodegenerative diseases
PROGRESS IN NEUROBIOLOGY; Año: 2018 vol. 162 p. 17 - 36
DOS-SANTOS-PEREIRA, MAURICIO; ACUÑA, LEONARDO; HAMADAT, SABAH; ROCCA, JEREMY; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; CHEHÍN, ROSANA; SEPULVEDA-DIAZ, JULIA; DEL-BEL, ELAINE; RAISMAN-VOZARI, RITA; MICHEL, PATRICK P.
Microglial glutamate release evoked by α-synuclein aggregates is prevented by dopamine
GLIA; Año: 2018 vol. 66 p. 2353 - 2365
VERA, CECILIA; ALVAREZ-OROZCO J.A.; MAIZA, A; CHANTEPIE, S; CHEHIN R; OUIDJA, O; PAPY-GARCIA D,
Heparan sulphates, amyloidosis and neurodegeneration
REVISTA DE NEUROLOGIA; Lugar: Barcelona; Año: 2017 vol. 16 p. 457 - 488
GONZÁLEZ-LIZÁRRAGA, FLORENCIA; SOCÍAS, SERGIO B.; ÁVILA, CÉSAR L.; TORRES-BUGEAU, CLARISA M.; BARBOSA, LEANDRO R. S.; BINOLFI, ANDRES; SEPÚLVEDA-DÍAZ, JULIA E.; DEL-BEL, ELAINE; FERNANDEZ, CLAUDIO O.; PAPY-GARCIA, DULCE; ITRI, ROSANGELA; RAISMAN-VOZARI, RITA; CHEHÍN, ROSANA N.
Repurposing doxycycline for synucleinopathies: Remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species
Scientific Reports; Año: 2017 vol. 7
AVILA, CÉSAR L.; CHAVES, SILVINA; SOCIAS, SERGIO B.; VERA-PINGITORE, ESTEBAN; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; VERA, CECILIA; PLOPER, DIEGO; CHEHÍN, ROSANA
Lessons learned from protein aggregation: toward technological and biomedical applications
Biophysical Reviews; Año: 2017 vol. 9 p. 501 - 515
CHAVES, SM; PERA, LM; AVILA CL; ROMERO, CM; BAIGORI, M; MORAN VIEYRA R; BORSARELLI, CD; CHEHÍN RN
Towards efficient biocatalysts: photo-immobilization of a lipase on a novel lysozyme amyloid-like nanofibrils
RSC Advances; Año: 2016 vol. 2016 p. 8528 - 8538
AVILA CL, TORRES-BUGEAU CM, BARBOSA LR, MORANDÉ SALES E, OUIDJA MO, SOCÍAS SB, CELEJ MS, RAISMAN-VOZARI R, PAPY-GARCIA D, ITRI R, CHEHIN RN
Structural Characterization of Heparin-induced GAPDH Protofibrils Preventing α-synuclein Oligomeric Species Toxicity
JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2014
VILLEGAS JM, TORRES-BUGEAU CM, CHEHÍN R, BURGOS MI, FIDELIO GD, RINTOUL MR, RAPISARDA VA
Maintenance and thermal stabilization of NADH dehydrogenase-2 conformation upon elimination of its C-terminal region
BIOCHIMIE; Lugar: Paris; Año: 2013 vol. 95 p. 382 - 387
VILLEGAS, JM; TORRES-BUGEAU CM; CHEHIN R; BURGOS, MI; FIDELIO, G; RAPISARDA VA
Maintenance and thermal stabilization of NADH dehydrogenase-2 conformation upon elimination of its C-terminal region
BIOCHIMIE; Lugar: Paris; Año: 2012
CABRERA, MA; FERREYRA, M.G; CORTEZ LM,; GRUPALLI, SA; ALVAREZ, LL; CHEHIN R
Amyloid detection using a peltier-based device
IEEE pulse; Lugar: Neueva York; Año: 2012 vol. 3 p. 58 - 65
TORRES-BUGEAU CM; AVILA CL,; RAISMAN-VOZARI R, ; PAPY-GARCIA D, ; ITRI R, ; BARBOSA LR,; CORTEZ LM,; SIM VL, ; CHEHÍN, R
Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication on α-synuclein aggregation.
JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2012 vol. 20 p. 2398 - 23409
CLARISA M. TORRES BUGEAU; CLAUDIO BORSARELLI; CARLOS MINAKH; CHEHÍN, ROSANA
The key role of membranes in amyloid formation from a biophysical perspective.
CURRENT PROTEIN AND PEPTIDE SCIENCE; Año: 2011 vol. 12 p. 166 - 180
CHALÓN M.; WILKE N; PEDERSEN J; RUFINI S; MORERO, R.D; CORTEZ L; CHEHÍN R.; FARIAS RICARDO N.; VINCENT P
Redox-active tyrosine residue in the microcin J25 molecule
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2011 p. 366 - 370
LEONARDO M. CORTEZ; CÉSAR L. ÁVILA; CLARISA M. TORRES BUGEAU; RICARDO N. FARÍAS; ROBERTO D. MORERO; ROSANA N. CHEHÍN
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE TETRAMER DISSOCIATION AND AMYLOID FIBRIL FORMATION INDUCED BY NEGATIVELY CHARGED MEMBRANES
FEBS LETTERS; Lugar: Netherlands; Año: 2010 vol. 584 p. 625 - 630
CORTEZ, LM; FARÍAS, R.N.; CHEHÍN, R.
Protective effect of 3,5,3’-triiodothyroacetic and 3,5,3’,5’-tetraiodothyroacetic acids on serum albumin fibrillation
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS; Lugar: Heidelber, Germany; Año: 2009 vol. 38 p. 857 - 863
AVILA, CL; ARCURI, BF; GONZALEZ NILO, FD; DE LAS RIVAS, J; CHEHIN, R; MORERO, RD
Role of electrostatics on membrane binding, aggregation and destabilization induced by NAD(P)H dehydrogenases. Implicance on membrane fusion.
BIOPHYSICAL CHEMISTRY; Año: 2008 vol. 137 p. 126 - 132
AVILA CL; RAPISARDA VA; FARIAS RN; DE LAS RIVAS J; CHEHIN R
Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases
BMC BIOINFORMATICS; Año: 2007 vol. 8 p. 1 - 8
CASTELLANO PATRICIA; VIGNOLO GRACIELA; FARÍAS RICARDO NORBERTO,; ARRONDO JOSÉ LUIS .; CHEHÍN ROSANA.
Interaction of lactocin 705 with lipid bilayer: a molecular view by FTIR spectroscopy
APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Año: 2007 vol. 73 p. 415 - 420
ILORO I; CHEHIN R; GONI FM; PAJARES MA; ARRONDO JL
Methionine adenosyltransferase alpha-helix structure unfolds at lower temperatures than beta-sheet: a 2D-IR study
BIOPHYSICAL JOURNAL; Lugar: Bethesda; Año: 2004 vol. 86 p. 3951 - 3958
RAPISARDA VA; CHEHÍN RN; DE LAS RIVAS J; RODRÍGUEZ-MONTELONGO L; FARÍAS RN; MASSA EM
Evidence for Cu(I)-thiolate ligation and prediction of a putative copper-binding site in the Escherichia coli NADH dehydrogenase-2.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS; Lugar: Amsterdam; Año: 2002 vol. 405 p. 87 - 94
CHEHIN R; RENGEL D; MILICUA JC; GONI FM; ARRONDO JL; PIFAT G
Early stages of LDL oxidation: apolipoprotein B structural changes monitored by infrared spectroscopy.
JLR PAPERS IN PRESS; Lugar: Bethesda; Año: 2001 vol. 42 p. 778 - 782
FARÍAS R; CHEHÍN R; CANELA R
Fourier-transformed infrared assay for the determination of positional specificity of non-specific and 1,3-specific lipases
BIOTECHNOLOGY LETTERS; Año: 2000 vol. 22 p. 905 - 908
CHEHÍN, R.; ISSÉ, B.; RINTOUL M.R.; FARÍAS R.N
Differential transmembrane diffusion of triiodothyronine and thyroxine in liposomes: regulation by lipid composition
JOURNAL OF MEMBRANE BIOLOGY; Año: 1999 vol. 167 p. 251 - 256
MARCOS M.J.; CHEHÍN, R.; ARRONDO J.L.R.; SHDAN G.; VILLAR E.; SHNYROV V
pH-dependent thermal transition of lentil lectin
FEBS LETTERS; Año: 1999 vol. 443 p. 192 - 196
CHEHÍN R; ILORO I.; MARCOS M.J; VILLAR E; SHNYROV V; Y ARRONDO JLR
Thermal and pH-induced conformational changes of a ƒÒ-sheet protein monitored by infrared spectroscopy
BIOCHEMISTRY; Año: 1999 vol. 38 p. 1527 - 1530
FLATMARK, T; ALMAS, B; KNAPPSKOG, P; BERGE, S; SVEBAK, M; CHEHÍN, R.; MUGA A; MARTINEZ A
Tyrosyne hydroxilase binds tetrahydrobiopterin cofactor with negative cooperative as shown by kinetics analyses and surface plasmon resonance detection
EUROPEAN JOURNAL OF BIOCHEMISTRY; Año: 1999 vol. 262 p. 840 - 849
ARCURI, B.F; VECHETTI, G.F.; CHEHIN, R.N.; GOÑI, F.M.; MORERO, R.D
Protein-induced fusion of phospholipid vesicles of heterogeneous sizes
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 1999 vol. 262 p. 586 - 590
CHEHÍN R.; ILORO I; ARRONDO J.L.R.
Thermal Denaturation of Membrane Proteins: an Infrared Study
Supramolecular Structure and Function; Año: 1998 vol. 100 p. 13 - 19
CHEHÍN R.; ILORO I; ARRONDO J.L.R.
Thermal Denaturation of Membrane Proteins: an Infrared Study
PERIODICUM BIOLOGORUM; Año: 1998 vol. 100 p. 13 - 19
CHEHÍN, R; THOROLFSSON, M; KNAPPSKOG, P; MARTINEZ A.; ARRONDO, J.L.; MUGA, A.
Domain structure and stability of human phenilalanine hydroxylase inferred from infrared spectroscopy
FEBS LETTERS; Año: 1998 vol. 422 p. 225 - 230
FARÍAS, R.N.; CHEHÍN, R.N.; RINTOUL, M.R.; MORERO, R.D.
Differential Effect of Triiodothyronine and Thyroxine on the Liposomal Membrane in Liquid Crystalline and Gel State
JOURNAL OF MEMBRANE BIOLOGY; Año: 1995 vol. 143 p. 135 - 141
CHEHÍN R; RINTOUL M; MORERO R; FARÍAS R
Differential effect of Triiodothyronine and Thyroxine on liposomes containing cholesterol: Physiological Speculations
JOURNAL OF MEMBRANE BIOLOGY; Año: 1995 vol. 147 p. 217 - 221