TOURVILLE, AURORE; VIGUIER, SARAH; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; TOMAS-GRAU, RODRIGO HERNÁN; RAMIREZ, PAOLA; BRUNEL, JEAN-MICHEL; DOS SANTOS PEREIRA, MAURICIO; DEL-BEL, ELAINE; CHEHIN, ROSANA; FERRIÉ, LAURENT; RAISMAN-VOZARI, RITA; FIGADÈRE, BRUNO; MICHEL, PATRICK PIERRE

Rescue of Dopamine Neurons from Iron-Dependent Ferroptosis by Doxycycline and Demeclocycline and Their Non-Antibiotic Derivatives

Antioxidants; Lugar: Basilea; Año: 2023 vol. 12

IGARTÚA, DANIELA E.; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; MARTINEZ, CAROLINA S.; ALONSO, SILVIA DEL V.; ÁVILA, CÉSAR L.; CHEHÍN, ROSANA; CHIARAMONI, NADIA S.; PRIETO, M. JIMENA

PAMAM dendrimers of generation 4.5 loaded with curcumin interfere with α-synuclein aggregation

OpenNano; Año: 2023 vol. 11

DE ATHAYDE MONCORVO COLLADO, A; SOCIAS, S.B.; GONZALEZ-LIZARRAGA, F.; PLOPER, D.; VERA PINGITORE, E.; CHEHIN, R.N.; CHAVES, S.

Magnetic amyloid-based biocatalyst for the hydrolysis of urea

FOOD CHEMISTRY; Lugar: Amsterdam; Año: 2023 vol. 433

TOMAS-GRAU, RODRIGO HERNÁN; MALDONADO-GALDEANO, CAROLINA; LÓPEZ, MÓNICA AGUILAR; PINGITORE, ESTEBAN VERA; AZNAR, PATRICIA; ALCORTA, MARÍA ELENA; VÉLEZ, EVA MARÍA DEL MAR; STAGNETTO, AGUSTÍN; SOLIZ-SANTANDER, SILVANA ESTEFANÍA; ÁVILA, CÉSAR LUÍS; SOCIAS, SERGIO BENJAMÍN; COSTAS, DARDO; CHAHLA, ROSSANA ELENA; PERDIGÓN, GABRIELA; CHEHÍN, ROSANA NIEVES; PLOPER, DIEGO; CAZORLA, SILVIA INÉS

Humoral immunoresponse elicited against an adenoviral-based SARS-CoV-2 coronavirus vaccine in elderly patients

Aging; Año: 2022 vol. 14 p. 7193 - 7205

TOMAS-GRAU, RODRIGO; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; PLOPER, DIEGO; AVILA, CÉSAR L.; SOCÍAS, SERGIO B.; BESNAULT, PIERRE; TOURVILLE, AURORE; MELLA, ROSA M.; VILLACÉ, PATRICIA; SALADO, CLARISA; ROSE, CLÉMENCE; SEON-MÉNIEL, BLANDINE; BRUNEL, JEAN-MICHEL; FERRIÉ, LAURENT; RAISMAN-VOZARI, RITA; MICHEL, PATRICK P.; FIGADÈRE, BRUNO; CHEHÍN, ROSANA

Neuroprotective Effects of a Novel Demeclocycline Derivative Lacking Antibiotic Activity: From a Hit to a Promising Lead Compound

Cells; Año: 2022 vol. 11

CHAHLA, ROSSANA ELENA; TOMAS-GRAU, RODRIGO HERNÁN; CAZORLA, SILVIA INÉS; PLOPER, DIEGO; VERA PINGITORE, ESTEBAN; LÓPEZ, MÓNICA AGUILAR; AZNAR, PATRICIA; ALCORTA, MARÍA ELENA; VÉLEZ, EVA MARÍA DEL MAR; STAGNETTO, AGUSTÍN; ÁVILA, CÉSAR LUÍS; MALDONADO-GALDEANO, CAROLINA; SOCIAS, SERGIO BENJAMÍN; HEINZE, DAR; NAVARRO, SILVIA ADRIANA; LLAPUR, CONRADO JUAN; COSTA, DARDO; FLORES, ISOLINA; EDELSTEIN, ALEXIS; KOWDLE, SHREYAS; PERANDONES, CLAUDIA; LEE, BENHUR; APFELBAUM, GABRIELA; MOSTOSLAVSKY, RAÚL; MOSTOSLAVSKY, GUSTAVO; PERDIGÓN, GABRIELA; CHEHÍN, ROSANA NIEVES

Long-term analysis of antibodies elicited by SPUTNIK V: A prospective cohort study in Tucumán, Argentina

The Lancet Regional Health - Americas; Año: 2022 vol. 6

DOMINGUEZ-MEIJIDE, ANTONIO; PARRALES, VALERIA; VASILI, EFTYCHIA; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; KÖNIG, ANNEKATRIN; LÁZARO, DIANA F.; LANNUZEL, ANNIE; HAIK, STÉPHANE; DEL BEL, ELAINE; CHEHÍN, ROSANA; RAISMAN-VOZARI, RITA; MICHEL, PATRICK P.; BIZAT, NICOLAS; OUTEIRO, TIAGO FLEMING

Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo

NEUROBIOLOGY OF DISEASE; Año: 2021 vol. 151 p. 105256 - 105275

MEDINA, LUCIANA; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; DOMINGUEZ-MEIJIDE, ANTONIO; PLOPER, DIEGO; PARRALES, VALERIA; SEQUEIRA, SABRINA; CIMA-OMORI, MARIA-SOL; ZWECKSTETTER, MARKUS; DEL BEL, ELAINE; MICHEL, PATRICK P.; OUTEIRO, TIAGO FLEMING; RAISMAN-VOZARI, RITA; CHEHÍN, ROSANA; SOCIAS, SERGIO B.

Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity

Frontiers in Aging Neuroscience; Año: 2021 vol. 13

FERREIRA JUNIOR, NILSON CARLOS; DOS SANTOS PEREIRA, MAURÍCIO; FRANCIS, NOUR; RAMIREZ, PAOLA; MARTORELL, PAULA; GONZÁLEZ-LIZARRAGA, FLORENCIA; FIGADÈRE, BRUNO; CHEHIN, ROSANA; DEL BEL, ELAINE; RAISMAN-VOZARI, RITA; MICHEL, PATRICK PIERRE

The chemically-modified tetracycline col-3 and its parent compound doxycycline prevent microglial inflammatory re-sponses by reducing glucose-mediated oxidative stress

Cells; Año: 2021 vol. 10

TOMAS-GRAU, RODRIGO HERNÁN; PLOPER, DIEGO; ÁVILA, CÉSAR LUIS; VERA PINGITORE, ESTEBAN; MALDONADO GALDEANO, CAROLINA; CHAVES, SILVINA; SOCIAS, SERGIO BENJAMÍN; STAGNETTO, AGUSTÍN; NAVARRO, SILVIA ADRIANA; CHAHLA, ROSSANA ELENA; AGUILAR LÓPEZ, MÓNICA; LLAPUR, CONRADO JUAN; AZNAR, PATRICIA; ALCORTA, MARÍA ELENA; COSTAS, DARDO; FLORES, ISOLINA; HEINZE, DAR; APFELBAUM, GABRIELA; MOSTOSLAVSKY, RAUL; MOSTOSLAVSKY, GUSTAVO; CAZORLA, SILVIA INÉS; PERDIGÓN, GABRIELA DEL VALLE; CHEHÍN, ROSANA

Elevated Humoral Immune Response to SARS-CoV-2 at High Altitudes Revealed by an Anti-RBD “In-House” ELISA

Frontiers in Medicine; Lugar: Lausane; Año: 2021 vol. 8

MACHÍN, BELÉN; CHAVES, SILVINA; ÁVILA, CÉSAR; PERA, LICIA MARÍA; CHEHÍN, ROSANA NIEVES; VERA PINGITORE, ESTEBAN

Highly reusable invertase biocatalyst: Biological fibrils functionalized by photocrosslinking

FOOD CHEMISTRY; Año: 2020 vol. 331

GONZÁLEZ-LIZÁRRAGA, FLORENCIA; PLOPER, DIEGO; ÁVILA, CÉSAR L.; SOCÍAS, SERGIO B.; DOS-SANTOS-PEREIRA, MAURICIO; MACHÍN, BELÉN; DEL-BEL, ELAINE; MICHEL, PATRICK PIERRE; PIETRASANTA, LÍA I.; RAISMAN-VOZARI, RITA; CHEHÍN, ROSANA

CMT-3 targets different α-synuclein aggregates mitigating their toxic and inflammogenic effects

Scientific Reports; Año: 2020 vol. 10 p. 1 - 17

ACUÑA, NULL; HAMADAT, NULL; CORBALÁN, NULL; GONZÁLEZ-LIZÁRRAGA, NULL; DOS-SANTOS-PEREIRA, NULL; ROCCA, NULL; DÍAZ, NULL; DEL-BEL, NULL; PAPY-GARCÍA, NULL; CHEHÍN, NULL; MICHEL, NULL; RAISMAN-VOZARI, NULL

Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates

Cells; Lugar: Lucerna; Año: 2019 vol. 8

BORTOLANZA, MARIZA; NASCIMENTO, GLAUCE C.; SOCIAS, SERGIO B.; PLOPER, DIEGO; CHEHÍN, ROSANA N.; RAISMAN-VOZARI, RITA; DEL-BEL, ELAINE

Tetracycline repurposing in neurodegeneration: focus on Parkinson’s disease

JOURNAL OF NEURAL TRANSMISSION. GENERAL SECTION.; Lugar: Viena; Año: 2018

SOCIAS, SERGIO B.; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; AVILA, CESAR L.; VERA, CECILIA; ACUÑA, LEONARDO; SEPULVEDA-DIAZ, JULIA E.; DEL-BEL, ELAINE; RAISMAN-VOZARI, RITA; CHEHIN, ROSANA N.

Exploiting the therapeutic potential of ready-to-use drugs: Repurposing antibiotics against amyloid aggregation in neurodegenerative diseases

PROGRESS IN NEUROBIOLOGY; Año: 2018 vol. 162 p. 17 - 36

DOS-SANTOS-PEREIRA, MAURICIO; ACUÑA, LEONARDO; HAMADAT, SABAH; ROCCA, JEREMY; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; CHEHÍN, ROSANA; SEPULVEDA-DIAZ, JULIA; DEL-BEL, ELAINE; RAISMAN-VOZARI, RITA; MICHEL, PATRICK P.

Microglial glutamate release evoked by α-synuclein aggregates is prevented by dopamine

GLIA; Año: 2018 vol. 66 p. 2353 - 2365

VERA, CECILIA; ALVAREZ-OROZCO J.A.; MAIZA, A; CHANTEPIE, S; CHEHIN R; OUIDJA, O; PAPY-GARCIA D,

Heparan sulphates, amyloidosis and neurodegeneration

REVISTA DE NEUROLOGIA; Lugar: Barcelona; Año: 2017 vol. 16 p. 457 - 488

GONZÁLEZ-LIZÁRRAGA, FLORENCIA; SOCÍAS, SERGIO B.; ÁVILA, CÉSAR L.; TORRES-BUGEAU, CLARISA M.; BARBOSA, LEANDRO R. S.; BINOLFI, ANDRES; SEPÚLVEDA-DÍAZ, JULIA E.; DEL-BEL, ELAINE; FERNANDEZ, CLAUDIO O.; PAPY-GARCIA, DULCE; ITRI, ROSANGELA; RAISMAN-VOZARI, RITA; CHEHÍN, ROSANA N.

Repurposing doxycycline for synucleinopathies: Remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species

Scientific Reports; Año: 2017 vol. 7

AVILA, CÉSAR L.; CHAVES, SILVINA; SOCIAS, SERGIO B.; VERA-PINGITORE, ESTEBAN; GONZÁLEZ-LIZÁRRAGA, FLORENCIA; VERA, CECILIA; PLOPER, DIEGO; CHEHÍN, ROSANA

Lessons learned from protein aggregation: toward technological and biomedical applications

Biophysical Reviews; Año: 2017 vol. 9 p. 501 - 515

CHAVES, SM; PERA, LM; AVILA CL; ROMERO, CM; BAIGORI, M; MORAN VIEYRA R; BORSARELLI, CD; CHEHÍN RN

Towards efficient biocatalysts: photo-immobilization of a lipase on a novel lysozyme amyloid-like nanofibrils

RSC Advances; Año: 2016 vol. 2016 p. 8528 - 8538

AVILA CL, TORRES-BUGEAU CM, BARBOSA LR, MORANDÉ SALES E, OUIDJA MO, SOCÍAS SB, CELEJ MS, RAISMAN-VOZARI R, PAPY-GARCIA D, ITRI R, CHEHIN RN

Structural Characterization of Heparin-induced GAPDH Protofibrils Preventing α-synuclein Oligomeric Species Toxicity

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2014

VILLEGAS JM, TORRES-BUGEAU CM, CHEHÍN R, BURGOS MI, FIDELIO GD, RINTOUL MR, RAPISARDA VA

Maintenance and thermal stabilization of NADH dehydrogenase-2 conformation upon elimination of its C-terminal region

BIOCHIMIE; Lugar: Paris; Año: 2013 vol. 95 p. 382 - 387

VILLEGAS, JM; TORRES-BUGEAU CM; CHEHIN R; BURGOS, MI; FIDELIO, G; RAPISARDA VA

Maintenance and thermal stabilization of NADH dehydrogenase-2 conformation upon elimination of its C-terminal region

BIOCHIMIE; Lugar: Paris; Año: 2012

CABRERA, MA; FERREYRA, M.G; CORTEZ LM,; GRUPALLI, SA; ALVAREZ, LL; CHEHIN R

Amyloid detection using a peltier-based device

IEEE pulse; Lugar: Neueva York; Año: 2012 vol. 3 p. 58 - 65

TORRES-BUGEAU CM; AVILA CL,; RAISMAN-VOZARI R, ; PAPY-GARCIA D, ; ITRI R, ; BARBOSA LR,; CORTEZ LM,; SIM VL, ; CHEHÍN, R

Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication on α-synuclein aggregation.

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2012 vol. 20 p. 2398 - 23409

CLARISA M. TORRES BUGEAU; CLAUDIO BORSARELLI; CARLOS MINAKH; CHEHÍN, ROSANA

The key role of membranes in amyloid formation from a biophysical perspective.

CURRENT PROTEIN AND PEPTIDE SCIENCE; Año: 2011 vol. 12 p. 166 - 180

CHALÓN M.; WILKE N; PEDERSEN J; RUFINI S; MORERO, R.D; CORTEZ L; CHEHÍN R.; FARIAS RICARDO N.; VINCENT P

Redox-active tyrosine residue in the microcin J25 molecule

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2011 p. 366 - 370

LEONARDO M. CORTEZ; CÉSAR L. ÁVILA; CLARISA M. TORRES BUGEAU; RICARDO N. FARÍAS; ROBERTO D. MORERO; ROSANA N. CHEHÍN

GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE TETRAMER DISSOCIATION AND AMYLOID FIBRIL FORMATION INDUCED BY NEGATIVELY CHARGED MEMBRANES

FEBS LETTERS; Lugar: Netherlands; Año: 2010 vol. 584 p. 625 - 630

CORTEZ, LM; FARÍAS, R.N.; CHEHÍN, R.

Protective effect of 3,5,3’-triiodothyroacetic and 3,5,3’,5’-tetraiodothyroacetic acids on serum albumin fibrillation

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS; Lugar: Heidelber, Germany; Año: 2009 vol. 38 p. 857 - 863

AVILA, CL; ARCURI, BF; GONZALEZ NILO, FD; DE LAS RIVAS, J; CHEHIN, R; MORERO, RD

Role of electrostatics on membrane binding, aggregation and destabilization induced by NAD(P)H dehydrogenases. Implicance on membrane fusion.

BIOPHYSICAL CHEMISTRY; Año: 2008 vol. 137 p. 126 - 132

AVILA CL; RAPISARDA VA; FARIAS RN; DE LAS RIVAS J; CHEHIN R

Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases

BMC BIOINFORMATICS; Año: 2007 vol. 8 p. 1 - 8

CASTELLANO PATRICIA; VIGNOLO GRACIELA; FARÍAS RICARDO NORBERTO,; ARRONDO JOSÉ LUIS .; CHEHÍN ROSANA.

Interaction of lactocin 705 with lipid bilayer: a molecular view by FTIR spectroscopy

APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Año: 2007 vol. 73 p. 415 - 420

ILORO I; CHEHIN R; GONI FM; PAJARES MA; ARRONDO JL

Methionine adenosyltransferase alpha-helix structure unfolds at lower temperatures than beta-sheet: a 2D-IR study

BIOPHYSICAL JOURNAL; Lugar: Bethesda; Año: 2004 vol. 86 p. 3951 - 3958

RAPISARDA VA; CHEHÍN RN; DE LAS RIVAS J; RODRÍGUEZ-MONTELONGO L; FARÍAS RN; MASSA EM

Evidence for Cu(I)-thiolate ligation and prediction of a putative copper-binding site in the Escherichia coli NADH dehydrogenase-2.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS; Lugar: Amsterdam; Año: 2002 vol. 405 p. 87 - 94

CHEHIN R; RENGEL D; MILICUA JC; GONI FM; ARRONDO JL; PIFAT G

Early stages of LDL oxidation: apolipoprotein B structural changes monitored by infrared spectroscopy.

JLR PAPERS IN PRESS; Lugar: Bethesda; Año: 2001 vol. 42 p. 778 - 782

FARÍAS R; CHEHÍN R; CANELA R

Fourier-transformed infrared assay for the determination of positional specificity of non-specific and 1,3-specific lipases

BIOTECHNOLOGY LETTERS; Año: 2000 vol. 22 p. 905 - 908

CHEHÍN, R.; ISSÉ, B.; RINTOUL M.R.; FARÍAS R.N

Differential transmembrane diffusion of triiodothyronine and thyroxine in liposomes: regulation by lipid composition

JOURNAL OF MEMBRANE BIOLOGY; Año: 1999 vol. 167 p. 251 - 256

MARCOS M.J.; CHEHÍN, R.; ARRONDO J.L.R.; SHDAN G.; VILLAR E.; SHNYROV V

pH-dependent thermal transition of lentil lectin

FEBS LETTERS; Año: 1999 vol. 443 p. 192 - 196

CHEHÍN R; ILORO I.; MARCOS M.J; VILLAR E; SHNYROV V; Y ARRONDO JLR

Thermal and pH-induced conformational changes of a ƒÒ-sheet protein monitored by infrared spectroscopy

BIOCHEMISTRY; Año: 1999 vol. 38 p. 1527 - 1530

FLATMARK, T; ALMAS, B; KNAPPSKOG, P; BERGE, S; SVEBAK, M; CHEHÍN, R.; MUGA A; MARTINEZ A

Tyrosyne hydroxilase binds tetrahydrobiopterin cofactor with negative cooperative as shown by kinetics analyses and surface plasmon resonance detection

EUROPEAN JOURNAL OF BIOCHEMISTRY; Año: 1999 vol. 262 p. 840 - 849

ARCURI, B.F; VECHETTI, G.F.; CHEHIN, R.N.; GOÑI, F.M.; MORERO, R.D

Protein-induced fusion of phospholipid vesicles of heterogeneous sizes

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 1999 vol. 262 p. 586 - 590

CHEHÍN R.; ILORO I; ARRONDO J.L.R.

Thermal Denaturation of Membrane Proteins: an Infrared Study

Supramolecular Structure and Function; Año: 1998 vol. 100 p. 13 - 19

CHEHÍN R.; ILORO I; ARRONDO J.L.R.

Thermal Denaturation of Membrane Proteins: an Infrared Study

PERIODICUM BIOLOGORUM; Año: 1998 vol. 100 p. 13 - 19

CHEHÍN, R; THOROLFSSON, M; KNAPPSKOG, P; MARTINEZ A.; ARRONDO, J.L.; MUGA, A.

Domain structure and stability of human phenilalanine hydroxylase inferred from infrared spectroscopy

FEBS LETTERS; Año: 1998 vol. 422 p. 225 - 230

FARÍAS, R.N.; CHEHÍN, R.N.; RINTOUL, M.R.; MORERO, R.D.

Differential Effect of Triiodothyronine and Thyroxine on the Liposomal Membrane in Liquid Crystalline and Gel State

JOURNAL OF MEMBRANE BIOLOGY; Año: 1995 vol. 143 p. 135 - 141

CHEHÍN R; RINTOUL M; MORERO R; FARÍAS R

Differential effect of Triiodothyronine and Thyroxine on liposomes containing cholesterol: Physiological Speculations

JOURNAL OF MEMBRANE BIOLOGY; Año: 1995 vol. 147 p. 217 - 221