Genetic analysis of the populations from Northern and Mesopotamian provinces of Argentina by means of 15 autosomal STRs

MIGUEL MARINO,; ANDREA SALA; DANIEL CORACH

FORENSIC SCIENCE INTERNATIONAL.

Elsevier

Lugar: Ireland; Año: 2006 vol. 160 p. 224 - 230

0379-0738

Genetic analysis of the populations from Northern and Mesopotamian provinces of Argentina by means of 15 autosomal STRs Miguel Marino, Andrea Sala and Daniel Corach, Servicio de Huellas Digitales Genéticas and Cátedra de Genética y Biología Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, 1113-Buenos Aires, Argentina Received 25 May 2005;  revised 12 July 2005;  accepted 18 July 2005.  Available online 31 August 2005. Abstract The allele frequencies for the 15 short tandem repeats included in the Power Plex-16 kit (Promega Corp., Madison, WI, USA) were determined in a sample of 429 unrelated individuals from five provinces of the Northern and Northeastern regions of Argentina. Three Northern provinces including Salta, Formosa and Chaco and two within the region surrounded by the Paraná and Uruguay Rivers commonly known as the Argentine Mesopotamia, including Misiones and Corrientes. Since in this region Entre Ríos Province is also present, previously published results were used for comparison. The calculated parameters: polymorphism information content (PIC); discrimination power (DP); matching probability (MP); typical paternity index (TPI) and power of exclusion (PE) showed Penta E to be the most valuable marker from the studied sample set. All loci met Hardy–Weinberg expectations using the Bonferroni correction for the number of loci analyzed, except D3S1358 in Salta and THO1 in Formosa provinces. Population differentiation test revealed that the Salta population sample data denoted significant differences for various loci when compared with the other province information presented here in, as well as with other published data sets. Keywords: Forensic sciences; Autosomal STR; Population genetics; Northern-Northeastern Argentina