INVESTIGADORES
ALONSO Daniel Fernando
artículos
Título:
Cirrhosis, von Willebrand factor (vWF) and the low incidence of metastatic malignancy in injured liver
Autor/es:
ALONSO DF
Revista:
EURASIAN JOURNAL OF MEDICINE
Editorial:
AVES YAYINCILIK LTD
Referencias:
Año: 2015 vol. 47 p. 229 - 230
ISSN:
1308-8734
Resumen:
The blood coagulation protein vWF is mainly secreted by endothelial cells into the subendothelial space and into the plasma, serving as an adhesive link between platelets and the vascular wall. It is known that liver sinusoidal endothelial cells are a prominent source of vWF, not only during hemostatic processess but also in tissue injury. Interestingly, many studies have implicated vWF as a key factor in resistance to metastasis.
