Metallic mass-produced materials as the basis of low-cost (bio)electroanalytical devices: pins, staples and thumbtacks

E. COSTA-RAMA; GONZÁLEZ-LÓPEZ, ANDREA; O. AMOR-GUTIÉRREZ; P. NANNI; GARCÍA-MIRANDA FERRARI, A.; NUÑEZ-BAJO, E.; R. MADRID; M.T. FERNÁNDEZ-ABEDUL

Conferencia; 18th International Conference on Electroanalysis ESEAC 2020; 2020

Nowadays, there is a widespread interest in developing miniaturized, simple and cheap platforms that produce fast and reliable responses. Electrochemical techniques fit perfectly with these purposes especially in combination with low-cost materials. Thus, in this work, we present innovative electrochemical devices based on the use of metallic mass-produced materials of common use such as pins, staples and thumbtacks.The use of stainless-steel pins for electroanalytical purposes has been recently introduced by Whitesides? group [1]. We have used them, as well as staples, to design different electroanalytical systems. In all the cases, a carbon-coated surface acted as working electrode (WE) and two bare pins, staples or wires as reference (RE) and counter (CE) electrodes. We have developed different pin-based electroanalytical systems: i) an enzymatic biosensor for glucose that uses a transparency sheet as support (Fig. 1A) [2], ii) a flow injection analysis (FIA) system for glucose determination in drinks [3], and iii) a batch injection (BIA) electroanalytical system for epinephrine determination in pharmaceuticals [4].On another note, chromatographic filter paper was combined with stainless-steel staples, used as electrodes (Fig. 1B), for the immunoelectrochemical detection of human tissue transglutaminase (related to celiac disease). Finally, an electrochemical cell, which includes carbon-coated thumbtacks (WE) and stainless-steel wires (RE and CE) (Fig. 1C), was also evaluated as a proof-of-concept for the design of novel low-cost electroanalytical platforms.References[1] A.C. Glavan et al., Lab Chip, 16 (2016) 112-119.[2] E.C. Rama et al., Biosens. Bioelectron., 88 (2017) 34-40.[3] E.C. Rama et al., Anal. Chem., 88 (2016) 9958-9963.[4] A. García-Miranda Ferrari et al., Sens. Actuator. B-Chem., 253 (2017) 1207-1213.