INVESTIGADORES
MILESI Maria Veronica
artículos
Título:
Insulina, Reactividad Vascular e Hipertensión Arterial
Autor/es:
REBOLLEDO A..; MILESI V.; RINALDI G; GRASSI DE GENDE AO
Revista:
MEDICINA (BUENOS AIRES)
Editorial:
MEDICINA (BUENOS AIRES)
Referencias:
Lugar: 56: 518-526. 1996.; Año: 1996 vol. 56 p. 518 - 526
ISSN:
0025-7680
Resumen:
Several epidemiological studies have shown that there is a relationship between hyperinsulinemia, insulin resistance and arterial hypertension. Insulin produces sympathetic nervous system stimulation, enhances renal sodium retention and it directly modifies vascular mechanisms involved in both contraction and relaxation of the vascular smooth muscle. These actions of insulin could lead either to elevation or reduction of blood pressure. The absence of vasodilation due to insulin resistance and/or the enhancement of the hypertensive effects due to hyperinsulinemia could be the link between insulin and hypertension.
