INVESTIGADORES
PERAL Maria De Los Angeles
artículos
Título:
EFFECTS OF ANGIOTENSIN I OF THE AMERICAN BULLFROG Rana Catesbeiana ON AMPHIBIAN TISSUES
Autor/es:
SORIA, M.; PROTO, MC; MARIA DE LOS ANGELES PERAL; COVIELLO, A; M, K.OSLA AND BUMPUS M
Revista:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. PART B, BIOCHEMISTRY & MOLECULAR BIOLOGY.
Editorial:
ELSEVIER, Sience .Inc.
Referencias:
Lugar: Inglaterra; Año: 1993 vol. 104 p. 113 - 336
ISSN:
1096-4959
Resumen:
1. The effect of bullfrog angiotensin I [Asp1, Val5, Asn9] angiotensin I, (AT I) on short-circuit current (SCC) on isolated toad skin and aorta contractility was examined. 2. AT I increased SCC in toad skin, the effect was partially inhibited by angiotensin-converting enzyme inhibitor (ACEI) teprotide. 3. AT I induced contractile responses in isolated rings of toad aorta. This effect was partially inhibited by captopril and completely blocked by the peptide antagonist [Sar1, Ile8] angiotensin II. 4. Present results indicate that this homologue AT I would act in amphibian tissues by conversion to AT II.
