INVESTIGADORES
PERAL Maria De Los Angeles
artículos
Título:
EFFECTS OF ANGIOTENSIN II ON ISOLATED TOAD (Bufo arenarum) AORTIC RINGS
Autor/es:
MARIA DE LOS ANGELES PERAL; COVIELLO, ALFREDO; CHIALVO, L.
Revista:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. PART B, BIOCHEMISTRY & MOLECULAR BIOLOGY.
Editorial:
ELSEVIER
Referencias:
Lugar: INGLATERRA; Año: 1988 vol. 90 p. 195 - 201
ISSN:
1096-4959
Resumen:
1. The vascular response to Asn1-Val5 angiotensin II (A II) in aortic rings from Bufo arenarum toad was studied. 2. Tachyphylaxis in response to A II could be abolished after incubation with norepinephrine (NE). 3. Phentolamine treatment partially inhibited the pressor effects to A II. 4. Sar1-Ile8 A II and Sar1-Ala8 A II significantly attenuated the vascular effects of A II and did not affect the NE response. 5. We conclude that the pressor response to A II has a direct contractile effect and a catecholamine dependent component in aortic rings of Bufo arenarum toad.
PMID: 2904859 [PubMed - indexed for MEDLINE]
