INVESTIGADORES
OTERO-LOSADA Matilde Estela
artículos
Título:
Exercise Ameliorates Endocrine Pancreas Damage Induced by Chronic Cola Drinking
Autor/es:
OTERO-LOSADA M; GONZALEZ J; MULLER A; OTTAVIANO G; CAO G; AZZATO F; AMBROSIO G; MILEI J
Revista:
PLOS ONE
Editorial:
PUBLIC LIBRARY SCIENCE
Referencias:
Lugar: San Francisco; Año: 2016
ISSN:
1932-6203
Resumen:
Purpose. This study evaluates whether the daily practice of an exercise routine might protect from endocrine pancreas damage in cola drinking rats.Methods. Forty-eight Wistar rats were randomly assigned to 4 groups depending on a) beverage consumption ad libitum, water (W) or cola beverage (C), and b) physical activity, sedentary (S) or treadmill running (R). Accordingly, 4 groups were studied: WS (water. sedentary), WR (water runner). CS (cola sedentary) and CR (cola runner). Body weight, nutritional data, plasma levels of glucose, creatinine, total cholesterol and cholesterol fractions, and triglycerides (enzymocolorimetry), and systolic blood pressure (plethysmography) were measured. After 6 months, euthanasia was performed (overdose sodium thiopental). Pancreatic tissue was immediately excised and conventionally processed for morphometrical and immunohistochemical determinations.Results. The effects of running and chronic cola drinking on pancreas morphology showed interaction (p
