INVESTIGADORES
GARGIULO Pascual Angel
artículos
Título:
Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons.-
Autor/es:
ACERBO, M.J.; GARGIULO, P.A.; KRUG, I.; DELIUS, J.D.
Revista:
BEHAVIOURAL BRAIN RESEARCH
Editorial:
Elsevier Science B.V.
Referencias:
Año: 2002 p. 171 - 171
ISSN:
0166-4328
Resumen:
Abstract Upon systemic administration of apomorphine, a potent dopamine agonist, pigeons show a bout of pecking behaviour. When the drug is repeatedly administered a sensitization takes place that is associated with pronounced discrimination learning. Here we show that intra-cerebral injections of apomorphine in the periphery of the nucleus accumbens of pigeons also elicit pecking. We additionally show that injections of 5-amino-phosphonohepatnoic acid, a NMDA-glutamate receptor blocker, into the Acc impairs the performance of a learned visual discrimination incorporating pecking as a choice response. We conclude that, as it is the case in mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. drug is repeatedly administered a sensitization takes place that is associated with pronounced discrimination learning. Here we show that intra-cerebral injections of apomorphine in the periphery of the nucleus accumbens of pigeons also elicit pecking. We additionally show that injections of 5-amino-phosphonohepatnoic acid, a NMDA-glutamate receptor blocker, into the Acc impairs the performance of a learned visual discrimination incorporating pecking as a choice response. We conclude that, as it is the case in mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. viour. When the drug is repeatedly administered a sensitization takes place that is associated with pronounced discrimination learning. Here we show that intra-cerebral injections of apomorphine in the periphery of the nucleus accumbens of pigeons also elicit pecking. We additionally show that injections of 5-amino-phosphonohepatnoic acid, a NMDA-glutamate receptor blocker, into the Acc impairs the performance of a learned visual discrimination incorporating pecking as a choice response. We conclude that, as it is the case in mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. visual discrimination incorporating pecking as a choice response. We conclude that, as it is the case in mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved. viour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area. # 2002 Elsevier Science B.V. All rights reserved.# 2002 Elsevier Science B.V. All rights reserved. Keywords: Pigeon; Nucleus accumbens; Pecking response; Learned discrimination; Glutamate antagonists; Dopamine agonist; SchizophreniaPigeon; Nucleus accumbens; Pecking response; Learned discrimination; Glutamate antagonists; Dopamine agonist; Schizophrenia