Is important the muscle health in the clinical assessment of risk of osteoporotic fractures?

DIAZ A; LERENA V; LUCAS S; OLIVERI B; DANILOWICZ D

Congreso; ANNUAL MEETING DE LA AMERICAN SOCIETY FOR BONE AND MINERAL RESEARCH; 2019

Objetive: To investigate the association between muscle mass and strength, bone mineral content and the incidence of osteoporotic fractures in ambulatory postmenopausal women ≥60 yo.Material and methods: A total of 577 women (69.9± 0.3) ≥60yo who attended a community activity in a University Hospital to evaluate osteoporotic risk and muscle health were included. Evaluation included a questionnaire about history of osteoporotic risk factors, chronic diseases, use of medication and fragility fractures, anthropometric measurements and physical performance tests: 4-meter walking speed [(Normal value (NV) < 5 s) and Chair sit-to-stand test (NV 20kg ). Body composition (by DXA, Lunar DPX) was performed in 292 participants. Statistical analysis done by SPSS20.0Results: Out of 577 women, 106 (18.3%) reported a fragility fracture. No differences in age, weight and height between fracture group and non-fracture group were found. Fracture group presented an altered walk speed test (p= 0.005, OR: 1.78, CI: 1.18-2.7) and altered hand grip strength (p= 0.041). Bone mineral content (BMC) either in the whole body as in selected regions like arms and legs, was significantly lower in the fracture group compared with the non-fracture group (7.39%, 9.75% and 6.94%, respectively, p