OLIVERI Maria Beatriz
congresos y reuniones científicas
Comparative plasmatic 25OHD vitamin D levels in institutionalized women older 65 years from Lteida City(Spain) and suburban Buenos Aires (Argentina)
Buenos Aires Argentina
Congreso; Reunión Anual de la Asociación Argentina de Osteología y Metabolismo Mineral; 2005
Institución organizadora:
Asociación Argentina de Osteología y Metabolismo Mineral
The prevalence of diseases related to aging has been increased during last century. Vitamin D status although is related to nutritional factors, it is mainly related to sun exposition because of its skin production. Vitamin D deficiency that leads to bone loss and an increment of osteoporotic fractures has been well documented, particularly in institutionalized elderly people from North and South hemispheres. Therefore, correction of vitamin D deficit will have an important impact on health care to reduce the incidence of morbidity and financial costs. In different latitude regions from Argentina it was also documented high prevalence of vitamin D insufficiency in urban healthy elderly people living at home, however, in Spain,.it has been traditionally considered that hypovitaminosis D it was not a common problem because of the high sun irradiation. The objective of the present work was to compare vitamin D status in women older than 65 years, with residence in geographic cities having similar sun irradiation index, Lleida City (Spain) (North Latitude 43 0) and San Isidro, suburban Buenos Aires area (South Latitude 340). The study was carried out during the end of the summer (years 2003-2004). A total of 81 women living in similar social status institutions were studied: 50 were residents in Lleida City and 31 in the Buenos Aires Province. The subjects gave a write inform concern to participate in the study during the usual health control care. Age, weight, height, clinical history and the frequency of sun exposition were recorded. None of the women was receiving vitamin D supplements or any medication that could affect bone and mineral metabolism. A dietary survey was carried out taken into account the weekly mean consumption of fish and dairy products. Fasting blood was obtained and the following laboratory determinations were carried out: hematocrit, red blood cell count, white blood cell count, haemoglobin, glucose, urea, uric acid, creatinine, cholesterol, total proteins, albumin, C reactive protein and 25-OH-D3 (radioimmunoassay, RIA, Diasorin). The results were: Lleida and Buenos Aires, respectively, (mean±standard deviation and ranges): Hb (g/dl): 12.6±2.4 (8.4-15.2); 13.1±1.4 (10-16.4); serum total protein (g/dl): 6.8±0.3 (5.8- 8.2); 6.8±0.6 (5.2-7.8); albumin (g/dl): 3.73±0.11 (2.9-4.5); 3.51±0.35 (2.7-4.1); Vitamin D (ng/ml): 11±6 (4-25); 12±6 (4-23). The percentage of women with 25-OH-D3 values lower than 10 ng/ml were: 50% in Lleida and 43% in Buenos Aires; the percentages increased to 76 y 71%, respectively, when the cut off point of 15 ng/ml was considered. Although a beautiful garden in both institutions, sun exposition was low in both groups. Dietary survey revealed greater fish consumption in Lleida City than in Buenos Aires (70 g/d vs. 22 g/d) but the red meat consumption was higher in Buenos Aires. Dairy products consumption was similar in both institutions, with a mean calcium intake of 800 mg/d, Vitamin D intake was 1.7 mg/d in Lleida, where dairy products are not fortified with vitamin D and 4mg/d in Buenos Aires, because of the consumption of fortified dairy products. Conclusions: these results show that in both countries vitamin D deficiency is important in this population group. Correction of this deficit would be imperative in order to have a positive impact on bone health of elderly people.