OLIVERI Maria Beatriz
congresos y reuniones científicas
Effect of vitamin D Nutritional status on muscle function and strenght in op/OP women over 65 years. A preliminary study
MASTAGLIA SR; SEIJO M; MUZIO D; CICERONE N; SOMOZA J; OLIVERI B
Congreso; XXIV Reunion Anual AAOMM; 2007
Vitamin D insufficiency has been associated with decreased muscle function and strength, and an increase in the risk of falls. The effects of vitamin D on bone health are well documented. However, the role of vitamin D in muscle function remains unclear. The aim of this work was to evaluate the effect of vitamin D nutritional status on muscle function in a group of women aged N65 years. Materials and methods: Fifty osteopenic/osteoporotic women aged (mean±DS) 70.8±5.0 years, body mass index (BMI) 27.1±4.0, and femoral neck (FN) bone mineral density (BMD) 0.732±0.07 g/cm2 (T-score −2.05±0.6) were studied. Patients receiving vitaminDsupplementation within 1 year prior to the study, presenting disease or taking medication affecting mineral metabolism, presenting neurological or motor diseases were excluded from the study. 25-hydroxyvitamin D (25OHD) values (RIA) were determined in fasting serum samples. Muscle function of lower limbs was assessed using walking speed tests, balance, and standsit tests, and muscle strength was determined using a dynamometer (Nicholas Manual Muscle TesterModel 01160). The study population was divided into 2 groups according to 25-hydroxyvitamin D (25OHD) ≷20 ng/ml. Group 1 (G1 n=24) N20 ng/ml, Group 2 (G2 n=26) b20 ng/ml. Results are G1 25OHD (ng/ml) 30.39±6.02 and G2 13.35±4.00 (pb0.001). The Muscle Function of lower limbs (Score) is G1 11.16±1.01 and G2 9.79±2.43; (pb0.05). No significant differences in muscle strength of lower limbs were observed between groups, except for the abductor muscles of the left hip. Conclusion: Levels of 25OHDN20 ng/ml seem to optimize lower limb muscle function.