INVESTIGADORES
KORNBLIHTT Alberto Rodolfo
artículos
Título:
Association of triiodothyronine binding activity to soluble adenylate cyclase in testicular preparations.
Autor/es:
KORNBLIHTT A; FLAWIÁ, M. M; DE MENDOZA D; GLIKIN, G. C; FARÍAS R; TORRES H N
Revista:
MOLECULAR AND CELLULAR BIOCHEMISTRY
Editorial:
SPRINGER
Referencias:
Año: 1981 p. 23 - 23
ISSN:
0300-8177
Resumen:
Cytosolic adenylate cyclase activity from rat seminiferous tubules was purified by chromtography in DEAE-cellulose, hydroxylapatite and Bio-Gel A-0.5 m as well as by centrifugation in sucrose gradients. In all these purification steps, fractions with adenylate cyclase activity also contained binding activity for L-T3. Binding studies indicate the existence of two L-T3 receptor components associated to adenylate cyclase activity. The component exhibiting the highest hormone affinity has the lowest binding capacity.