INVESTIGADORES
KORNBLIHTT Alberto Rodolfo
artículos
Título:
Chromatin, transcript elongation and alternative splicing
Autor/es:
KORNBLIHTT, A
Revista:
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Editorial:
NATURE PUBLISHING GROUP
Referencias:
Año: 2006 vol. 13 p. 5 - 5
ISSN:
1545-9985
Resumen:
Alternative splicing can be regulated by the rate and pausing of transcriptional elongation. A new study reveals that the chromatin remodeling factor SWI/SNF regulates alternative splicing by creating internal “road blocks” to elongation where the phosphorylation status of RNA pol II is qualitatively changed.