INVESTIGADORES
CASTELLANOS Lucia Ines
artículos
Título:
Gluconic acid produced by Gluconacetobacter diazotrophicus PAL5 possesses antimicrobial properties
Autor/es:
NIETO PEÑALVER C.; SAVINO M.; BERTINI E; SANCHEZ L.; CASTELLANOS DE FIGUEROA, LUCÍA INÉS
Revista:
RESEARCH IN MICROBIOLOGY
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2014 vol. 165 p. 549 - 558
ISSN:
0923-2508
Resumen:
Gluconic acid is produced in large quantities by the endophytic and diazotrophic bacterium Gluconacetobacter diazotrophicus Pal5. This organic acid derives from direct oxidation of glucose by a pyrroloquinoline-quinone-linked glucose dehydrogenase in this plant growth promoting bacterium. In the present article, evidence is presented showing that gluconic acid is also responsible for the antimicrobial activity of G. diazotrophicus Pal5. The broad antagonistic spectrum includes Gram-positive and negative bacteria. Eukaryotic microorganisms are more resistant to growth inhibition by this acid. Inhibition by gluconic acid can be modified through the presence of other organic acids. In contrast to other microorganisms, the Quorum Sensing system of G. diazotrophicus Pal5, a regulatory mechanism that plays a key role in several microbeemicrobe interactions, is not related to gluconic acid production and the concomitant antagonistic activity.
