CIBICI 14215
CENTRO DE INVESTIGACION EN BIOQUIMICA CLINICA E INMUNOLOGIA
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Functional differences in regulatory t cells from mice with different susceptibility to the development of autoimmune diseases
Autor/es:
OLIVERA, CAROLINA; RIVERO, VIRGINIA E.; SALAZAR, FLORENCIA C.; MOTRICH, RUBEN D.; GODOY, GLORIA J.
Lugar:
Buenos Aires
Reunión:
Congreso; Reunion Conjunta de sociedades en Biociencias; 2017
Institución organizadora:
Sociedad Argentina de Inmunología (SAI), entre otras
Resumen:
NOD mice are characterized by their highly susceptibility to develop spontaneous and induced autoimmune diabetes, thyroiditis, sialiditis and prostatitis. It has been suggested that this increased susceptibility could be related to defects in the number and/or functionality in regulatory T cell (Treg) populations. In a previous work, we have shown that NOD mice exhibited significantly lower frequencies, absolute Treg numbers and mean fluorescence intensity (MFI) for Foxp3, when compared with other mice strains (p
