NEUTROPHILS RECRUITMENT MODULATES T CELL RESPONSE IN LYMPH NODES

CASTELL, SOFÍA D; HARMAN, MARÍA F; GORLINO, CAROLINA V; MORÓN, VICTOR G; MALETTO, BELKYS A; PISTORESI, MARÍA C

Buenos Aires

Congreso; IV LASID Meeting - LXIII Argentinean Society for Immunology Meeting - II French-Argentinean Immunology Meeting; 2015

LASID - SAI

Previously we demonstrated that when mice were immunized with OVA emulsified in Freund?s complete adjuvant on day 0, boosted with OVA emulsified in Freund?s incomplete adjuvant on day 15, and 10 days after injected with OVA-FITC in the footpad, the main OVA-FITC+ cells recruited in draining popliteal lymph nodes (D-poLNs) were neutrophils whereas these cells were undetectable on control popliteal lymph nodes (ND-poLNs) corresponding to the footpad injected with saline solution (D-poLNs 9,9±2% vs. ND-poLNs 0,3±0,1%; p