CIBICI   14215
CENTRO DE INVESTIGACION EN BIOQUIMICA CLINICA E INMUNOLOGIA
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Galectina-3 regulates germinal center formation, autoreactive and long-lived antibody response
Autor/es:
BECCARIA CRISTIAN G;; AMEZCUA VESELY MC; FIOCCA VEMENGO F; GOROSITO- SERRAN M; RAMELLO MC; TOSELLO BOARI J; MUCCI J; CAMPETELLA O; MONTES CL; ACOSTA RODRIGUEZ EV; GRUPPI A
Reunión:
Congreso; LIX Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica. LXII Reunión Anual de la Sociedad Argentina de Inmunologia; 2014
Resumen:
We previously observed that B cells undergoing differentiation to antibody-secreting cells (ASC) downregulate the expression of Gal3 and that inhibition increases terminal B cell differentiation. In agreement, we observed that Gal3 knock-out (KO) mice showed a higher frequency of IgM and IgG ASC (p