CIBICI   14215
CENTRO DE INVESTIGACION EN BIOQUIMICA CLINICA E INMUNOLOGIA
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
IMMUNOMODULATORY FUNCTION OF CD11B+GR1+ MYELOID CELLS FROM AGED MICE
Autor/es:
HARMAN, MARÍA F ; CASTELL, SOFÍA D ; GORLINO, CAROLINA V ; MALETTO, BELKYS A ; MORÓN, GABRIEL ; PISTORESI, MARÍA C
Lugar:
Los Cocos, Córdoba
Reunión:
Congreso; LXI REunión Anual de la Sociedad Argentina de Inmunología; 2013
Institución organizadora:
Sociedad Argentina de Inmunología
Resumen:
We have previously demonstrated that administration of CpG-ODN emulsified in IFA (CpG-ODN+IFA) to 3 (young) and 18 (aged) month-old mice induces an accumulation of CD11b+Gr1+ myeloid cells, with immunoregulatory function in the spleen. In this study, we intended to characterize CD11b+Gr1+ isolated from aged CpG-ODN+IFA-treated mice. Ten days after administration of CpG-ODN+IFA, CD11b+Gr1+ myeloid cells from aged mice expressed higher levels of the myeloid lineage differentiation and maturation markers CD31 and CD124 compared to cells from non-treated mice (p