CIBICI 14215
CENTRO DE INVESTIGACION EN BIOQUIMICA CLINICA E INMUNOLOGIA
Unidad Ejecutora - UE
artículos
Título:
THE THYROID HORMONE TRIIODOTHYRONINE REINVIGORATES DENDRITIC CELLS AND POTENTIATES ANTI-TUMOR IMMUNITY
Autor/es:
MONTESINOS MM; RABINOVICH GA; ALAMINO VA; PELLIZAS CG
Revista:
OncoImmunology
Editorial:
Taylor & Francis
Referencias:
Lugar: Oxfordshire; Año: 2016 vol. 5 p. 1 - 3
Resumen:
Dendritic cell (DC) cancer vaccines have shown limited clinical benefit. Thus, the identification of signals and molecular pathways that potentiate the immunogenicity of DCs has become a major challenge in cancer research. Our studies demonstrate that triiodothyronine endows DCs with enhanced ability to stimulate cytotoxic T-cell responses with implications in DC-based immunotherapy.
