CIBICI   14215
CENTRO DE INVESTIGACION EN BIOQUIMICA CLINICA E INMUNOLOGIA
Unidad Ejecutora - UE
artículos
Título:
Neurocandidiasis, definiendo las interacciones patogeno huésped en este particular sitio del organismo.
Autor/es:
FIGUEREDO CM; RENNA MS; CEJAS H; SOTOMAYOR CE
Revista:
Alergia e Inmunologia Clinica
Referencias:
Año: 2007 vol. 24 p. 86 - 96
ISSN:
0328-2872
Resumen:
The colonization of the Central Nervous System by Candida albicans or other candida species, is a few frecuent fact but with a high risk for the host. The morbidity and mortality associated with these mycosis and the absence of successfull treatment, make a darkness issue for this disease. Other factors that make more complex this scenary are the charasteristic of this opportunistyc fungus and the particulary biological niche. In the present article we revised several important aspects about the etiological agent and the strategies of agression/ evassion involved during the host-fungal interaction. Also we reffer to the particulary place considered as an immune privileged site, the network of cells and mediators involved in this phenomenon and its impact in the evolution of the infection. The current challenged issued of CNS candidiasis are the diagnosis, the development of successful treatment and prommotion of new strategies and all these facts call interdisciplinary interactions between investigators of different areas.