CONICET | Buscador de Institutos y Recursos Humanos

In non-invasive thermal diagnostics, accurate correlations between the thermal image on skin surface and interior human pathophysiology are often desired, which require general solutions for the bioheat equation. In this paper, a diﬀerence scheme for the Pennes with a space-dependent thermal physiological parameters and convec- tive boundary condition on the top surface, was used to approximate the solution. Details computations indicated that the thermal states of biological bodies, reﬂect- ing physiology conditions, could be correlated to the temperature mapping recorded at the skin surface. The eﬀect of the skin emisity, the convective heat transfer coef- ﬁcient and the temperature of the sourranding air, the metabolic rate and the blood perfusion rate in the tumor, and the tumor size and number on the sensitivity of the thermography are comprehensivily investigated. Moreover the inverse problems consisting in the simultaneous estimation of unknow geometrical parameters (loca- tion size) of the tumor are solved. On the stage of numerical solution the pattern search algorithm coupled with the diﬀerence scheme has been applied.