Role of MicroRNA miR319 in Plant Development

SCHOMMER C; BRESSO EG; SPINELLI SV; PALATNIK JF

MicroRNAs in Plant Development and Stress Responses

Springer Berlin Heidelberg

Lugar: Heidelberg; Año: 2012; p. 29 - 47

Originally identified in a genetic screen, microRNA miR319 regulates transcription factors of the TCP family. The balance between miR319 and its targets controls leaf morphogenesis and several other plant developmental processes. High levels of miR319 or low TCP activity causes an excess of cell proliferation that generates a crinkled simple leaf in Arabidopsis and snapdragon or supercompound organ in tomato. In contrast, reduced miR319 levels or high TCP activity reduces leaf and petal size, results in a simple tomato leaf, and is lethal in extreme cases. Insights into the gene networks that are controlled by the miR319-regulated TCPs demonstrate their participation in multiple biological pathways, from hormone biosynthesis and signaling to cell proliferation and differentiation.