IBR 13079
INSTITUTO DE BIOLOGIA MOLECULAR Y CELULAR DE ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Transcriptional control by G-quadruplexes: in vivo roles and perspectives for specific intervention
Autor/es:
DAVID, A; ARMAS, P; CALCATERRA NB
Revista:
Transcription
Editorial:
Taylor & Francis
Referencias:
Año: 2017 vol. 8 p. 21 - 25
ISSN:
2154-1264
Resumen:
G-quadruplexes are non-canonical DNA secondary structures involved in several genomic and molecular processes. Here we summarize the main G-quadruplex features and evidences proving the in vivo role on the transcriptional regulation of genes required for zebrafish embryonic development. We also discuss alternative strategies for specifically interfering G-quadruplex in vivo.
