IBR   13079
INSTITUTO DE BIOLOGIA MOLECULAR Y CELULAR DE ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Integration of Temperature and Blue-Light Sensing in Acinetobacter baumannii Through the BlsA Sensor
Autor/es:
GOLIC, ADRIÁN E.; MORÁN VIEYRA, FAUSTINO E.; BORSARELLI, CLAUDIO D.; GOLIC, ADRIÁN E.; MORÁN VIEYRA, FAUSTINO E.; BORSARELLI, CLAUDIO D.; VALLE, LORENA; CABRUJA, MATÍAS; MUSSI, MARÍA ALEJANDRA; VALLE, LORENA; CABRUJA, MATÍAS; MUSSI, MARÍA ALEJANDRA; ABATEDAGA, INÉS; MÜLLER, GABRIELA L.; JAIME, PAULA C.; ABATEDAGA, INÉS; MÜLLER, GABRIELA L.; JAIME, PAULA C.
Revista:
PHOTOCHEMISTRY AND PHOTOBIOLOGY
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Año: 2017 vol. 93 p. 805 - 814
ISSN:
0031-8655
Resumen:
BlsA is a BLUF photoreceptor present in Acinetobacter baumannii, responsible for modulation of motility, biofilm formation and virulence by light. In this work, we have combined physiological and biophysical evidences to begin to understand the basis of the differential photoregulation observed as a function of temperature. Indeed, we show that blsA expression is reduced at 37°C, which correlates with negligible photoreceptor levels in the cells, likely accounting for absence of photoregulation at this temperature. Another point of control occurs on the functionality of the BlsA photocycle itself at different temperatures, which occurs with an average quantum yield of photoactivation of the signaling state of 0.20 ± 0.03 at 15°C