Complete Sequence of a blaNDM-1-Harboring Plasmid in an Acinetobacter bereziniae Clinical Strain Isolated in Argentina

BROVEDAN MARCO; MARCHIARO PATRICIA ; MORÁN-BARRIO JORGELINA ; CAMERANESI MARCELA ; CERA GABRIELA ; RINAUDO MARIÁNGEL ; VIALE ALEJANDRO M.; LIMANSKY ADRIANA S.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

AMER SOC MICROBIOLOGY

Lugar: Washington; Año: 2015 vol. 59 p. 6667 - 6669

0066-4804

The New Delhi metallo--lactamase (NDM-1) was initiallyidentified in clinical isolates of Escherichia coli and Klebsiellapneumoniae in Sweden from a patient previously hospitalized inIndia (1). Since then, blaNDM-1 has frequently been reported inEnterobacteriaceae and Acinetobacter spp., with a fast disseminationin the Indian subcontinent, the Balkan countries, China, andthe Middle East (2). NDM-1 producers generally associated withEnterobacteriaceae species have also been reported, albeit withmuch lower frequency, in Latin American countries, includingGuatemala, Mexico, Colombia, and Brazil (3). Moreover, productionof NDM-1 in this geographic region has also been noted inAcinetobacter baumannii in Honduras and Brazil (3, 4) and inAcinetobacter pittii in Paraguay and Brazil (5, 6). Here, we reportthe first case of an NDM-1-producing Acinetobacter species inArgentina, an Acinetobacter bereziniae clinical isolate. We describealso the complete sequence of a blaNDM-1-containing plasmid inthis strain.