IFLP   13074
INSTITUTO DE FISICA LA PLATA
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Constructing the Average Natural History of HIV-1 Infection
Autor/es:
L. DIAMBRA; A. CAPURRO; C.P. MALTA
Lugar:
Mar del Plata, Argentina
Reunión:
Conferencia; Nonequilibrium Statistical Mechanics and Nonlinear Physics, XV Conference; 2006
Resumen:
Many aspects of the natural course of the HIV-1 infection remains unclear, despite important efforts towards understanding its long-term dynamics. Using a scaling approach that places progression markers (viral load, CD4+, CD8+) of many individuals on a single average natural course of disease progression, we introduce the concept of inter-individual scaling and time scaling. Our quantitative assessment of the natural course of HIV-1 infection indicates that the dynamics of the evolution for the individual that developed AIDS (opportunistic infections) is different from that of the individual that did not develop AIDS. This means that the rate of progression is not relevant for the infection evolution.
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