IDIM   12530
INSTITUTO DE INVESTIGACIONES MEDICAS
Unidad Ejecutora - UE
artículos
Título:
Incentive relativity in middle aged rats
Autor/es:
JUSTEL, N.; MUSTACA, A. E.; BOCCIA, M.; RUETTI, E.
Revista:
NEUROSCIENCE LETTERS
Editorial:
ELSEVIER IRELAND LTD
Referencias:
Lugar: Ireland; Año: 2014 vol. 559 p. 122 - 126
ISSN:
0304-3940
Resumen:
Response to a reinforcer is affected by prior experience with different reward values of that reward, a phenomenon known as incentive relativity. Two different procedures to study this phenomenon are the incentive downshift (ID) and the consummatory anticipatory negative contrast (cANC), the former is an emotional-cognitive protocol and the latter cognitive one. Aged rodents, as also well described in aged humans, exhibit alterations in cognitive functions. The main goal of this work was to evaluate the effect of age in the incentive? assessment using these two procedures. The results indicated that aged rats had an adequate assessment of the rewards but their performance is not completely comparable to that of young subjects. They recover faster from the ID and they had a cognitive impairment in the cANC. The results are discussed in relation to age-related changes in memory and emotion.