CIHIDECAR   12529
CENTRO DE INVESTIGACIONES EN HIDRATOS DE CARBONO
Unidad Ejecutora - UE
artículos
Título:
Facile synthesis of methyl beta- and alfa-O-D-[6-3H]galactofuranosides from D-galacturonic acid. Substrates for detection of galactofuranosidases
Autor/es:
A. BORDONI; C. LIMA; R. M. DE LEDERKREMER; C. MARINO
Revista:
CARBOHYDRATE RESEARCH
Editorial:
Elsevier
Referencias:
Año: 2008 p. 1863 - 1869
ISSN:
0008-6215
Resumen:
Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl alfa,beta-D-galactofuranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases.