CIHIDECAR 12529
CENTRO DE INVESTIGACIONES EN HIDRATOS DE CARBONO
Unidad Ejecutora - UE
artículos
Título:
Myriaporones 1-4, Cytotoxic Metabolites from the Mediterranean Bryozoan Myriapora
Autor/es:
JIE-FEI CHENG,* JONG-SOO LEE, RYUICHI SAKAI, ELIZABETH A. JARES-ERIJMAN, MARIA V. SILVA, AND KENNETH L. RINEHART
Revista:
JOURNAL OF NATURAL PRODUCTS
Referencias:
Año: 2007 vol. 70 p. 332 - 336
ISSN:
0163-3864
Resumen:
Four novel polyketide-derived metabolites, myriaporones 1, 2, 3, and 4, have been isolated from the Mediterranean
bryozoan Myriapora truncata. Their structures and stereochemistry have been assigned from the analysis of spectroscopic data. The inseparable equilibrium mixture of myriaporones 3 and 4 showed 88% inhibition of L1210 murine leukemia cells at 0.2 micrograms/mL.
