INQUIMAE   12526
INSTITUTO DE QUIMICA, FISICA DE LOS MATERIALES, MEDIOAMBIENTE Y ENERGIA
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
VarQ: an automatic tool for the structural analysis of nsSNPs
Autor/es:
JAVIER DELGADO; LUIS SERRANO PUBUL ; LEANDRO G. RADUSKY; MARCELO A. MARTÍ; CHRISTINA KIEL; ADRIAN TURJANSKI
Lugar:
Orlando
Reunión:
Congreso; Intelligent Systems for Molecular Biology; 2016
Institución organizadora:
International Society for Computational Biology
Resumen:
Predicting the detailed effects of variants on the structure and function of a protein is a critical problem to be solved in drug discovery and personalized medicine. Thesevariants can influence drug selection and provoke a variety of effects on the protein behavior A considerable portion of variants effects will result in subtle phenotypiceffects that are challenging to predict. VarQ was developed with the aim of giving to the user a full description of the properties of each variation, extracting knownvariants from reference databases and allowing the user to specify a set novel variations to be analyzed.
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