A pipeline for structural annotations in bacterial genomes

LANZAROTTI, ESTEBAN; DEFELIPE, LUCAS ALFREDO; RADUSKY, LEANDRO G; MARTI, MARCELO ADRIÁN; TURJANSKI, ADRIAN GUSTAVO

Oro Verde

Congreso; 3 er Congreso Argentino de Bioinformática y Biología Computacional; 2012

Asociación Argentina de Bioinformática y Biología Computacional

In the last 10 years, a lot of work was done in developing software tools for predicting of structural features from a protein amino acid sequence, like: secondary structure[1], intrinsic disorder[2] and tertiary structure[3]. Also, a lot of effort was spent in the improvement DNA sequencing technologies, making possible to obtain many portions of bacterial DNA without waiting any longer[4]. In this work we present a pipeline to produce annotations of structural properties for sequenced bacterial proteins and to produce structural models using homology modeling techniques and assesing models using two quality measures.