INQUIMAE 12526
INSTITUTO DE QUIMICA, FISICA DE LOS MATERIALES, MEDIOAMBIENTE Y ENERGIA
Unidad Ejecutora - UE
capítulos de libros
Título:
A Practical Guide: Uncaging with Visible Light, Inorganic Caged Compounds
Autor/es:
LEONARDO ZAYAT; LUIS M. BARALDO; ROBERTO ETCHENIQUE
Libro:
Imaging in Neuroscience and Development: A Laboratory Manual
Editorial:
Cold Spring Harbor Laboratory Press
Referencias:
Año: 2010;
Resumen:
We present in this chapter a new strategy to uncage biologically active molecules based in the photochemistry of coordination complexes. Complexes containing the Ruthenium-bipyridine core are efficient photoactive cages for amines, including several neurotransmiters and analogs as GABA, Glutamate, Serotonin, Nicotine and 4-aminopyridine. The uncaging process occurs with visible light, up to 532 nm, and also with IR light (800 nm) in two-photon regime.
