INQUIMAE   12526
INSTITUTO DE QUIMICA, FISICA DE LOS MATERIALES, MEDIOAMBIENTE Y ENERGIA
Unidad Ejecutora - UE
artículos
Título:
Electrochemical investigations into host-guest interactions of a natural antioxidant compound with beta-cyclodextrin
Autor/es:
F.D, FERREIRA; E.G. DA SILVA; L.P. MENDEZ DE LEO; E.J. CALVO; E. DE SOUZA BENTOA; M. OLIVEIRA FONSECA GOULARTA; F. CAXICO DE ABREUA
Revista:
ELECTROCHIMICA ACTA
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2010 vol. 56 p. 797 - 803
ISSN:
0013-4686
Resumen:
The electrochemical behavior of mangiferin (MGN), a natural antioxidant compound, is examined using
cyclic and differential pulse voltammetry in a protic medium on a glassy carbon electrode. The voltammograms
exhibit a single irreversible pH-dependent anodic wave with current controlled by adsorption.
Complexes of MGN with -cyclodextrin (-CD) were prepared and their formation was confirmed by
UVvis spectroscopy and electrochemical experiments, using a self-assembled monolayer of cyclodextrin
on a gold electrode. The association constant of MGN:-CD complexes was estimated by the
BenesiHildebrand method, based on the spectrophotometric quantification of free -CD and by the
direct method using cyclic voltammetry and the Langmuir isotherm.
PM IRRAS experiments corroborated the inclusion process based on the observation of the corresponding
peaks in the spectra of the samples.
MGN was quantified using a simple electrochemical method based on a -CD incorporated carbon
nanotube (CNT)-modified electrode (-CDCNT). The presence of -CD led to a 10-fold lower detection
limit than that obtained with a CNT-modified electrode.