INQUIMAE   12526
INSTITUTO DE QUIMICA, FISICA DE LOS MATERIALES, MEDIOAMBIENTE Y ENERGIA
Unidad Ejecutora - UE
artículos
Título:
Electrochemical investigations into host-guest interactions of a natural antioxidant compound with beta-cyclodextrin
Autor/es:
F.D, FERREIRA; E.G. DA SILVA; L.P. MENDEZ DE LEO; E.J. CALVO; E. DE SOUZA BENTOA; M. OLIVEIRA FONSECA GOULARTA; F. CAXICO DE ABREUA
Revista:
ELECTROCHIMICA ACTA
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2010 vol. 56 p. 797 - 797
ISSN:
0013-4686
Resumen:
The electrochemical behavior of mangiferin (MGN), a natural antioxidant compound, is examined using cyclic and differential pulse voltammetry in a protic medium on a glassy carbon electrode. The voltammograms exhibit a single irreversible pH-dependent anodic wave with current controlled by adsorption. Complexes of MGN with -cyclodextrin (-CD) were prepared and their formation was confirmed by UVĀ–vis spectroscopy and electrochemical experiments, using a self-assembled monolayer of cyclodextrin on a gold electrode. The association constant of MGN:-CD complexes was estimated by the BenesiĀ–Hildebrand method, based on the spectrophotometric quantification of free -CD and by the direct method using cyclic voltammetry and the Langmuir isotherm. PM IRRAS experiments corroborated the inclusion process based on the observation of the corresponding peaks in the spectra of the samples. MGN was quantified using a simple electrochemical method based on a -CD incorporated carbon nanotube (CNT)-modified electrode (-CDCNT). The presence of -CD led to a 10-fold lower detection limit than that obtained with a CNT-modified electrode.