INQUIMAE   12526
INSTITUTO DE QUIMICA, FISICA DE LOS MATERIALES, MEDIOAMBIENTE Y ENERGIA
Unidad Ejecutora - UE
artículos
Título:
10000 times volume reduction for fluorescence correlation spectroscopy using nano-antennas
Autor/es:
ESTRADA, LAURA C.; PEDRO F. ARAMEND√ćA; MART√ćNEZ. OSCAR E.
Revista:
OPTICS EXPRESS
Referencias:
Año: 2008
ISSN:
1094-4087
Resumen:
We present an experimental and theoretical study of a new scheme for Near-Field Fluorescence Correlation Spectroscopy that, using the field enhancement by optical nanoantennas, allows the reduction of the observation volume 4 orders of magnitude below the diffraction limit. This reduction can be used in two different ways: to increase the sample concentration and to improve the spatial resolution of the dynamics under study. Our experimental results using individual gold nanoparticles and a 150M Rose Bengal solution in glycerol confirm the volume reduction.