Treatment of irradiated mice with oral Genuine ESSIAC tea as a DNA damage protector attenuate insult.

LEONEL MONDRAGON; FAVANT JOSE LUIS; MARTINEZ MARIGNAC VERONICA L

OTTAWA

Conferencia; CANADIAN CANCER RESEARCH CONFERENCE; 2019

CANADIAN CANCER RESEARCH ALLIANCE

Genuine Essiac tea has been used widely in the homeopathy market as a popular anticancer and antioxidant tonic. Due to the reported ROS scavenging properties of Essiac formula, weevaluate DNA damaged mitigation in Balb/c male mice under 25-100mSv-Gy, which is an annual average effective dose received by most X Ray exam services personnel. The tea formularesulted in a significant reduction of DNA damaged of mice under the formula evidenced by Comet Assay and micronucleous as well as in a normalization of the complete blood count (CBC). Thetea did not show any genotoxicity at the used doses. We not only demonstrated that Essiac tea is not toxic and acts as a radioprotector of IR X rays at doses use in image exams though we alsooptimized a murine model for further analysis of other natural compounds and supplements.