IIBBA 05544
INSTITUTO DE INVESTIGACIONES BIOQUIMICAS DE BUENOS AIRES
Unidad Ejecutora - UE
artículos
Título:
ETAA1 ensures proper chromosome segregation: A matter of S phase or mitosis?
Autor/es:
GOTTIFREDI, VANESA; GONZĂLEZ BESTEIRO, MARINA ALEJANDRA
Revista:
JOURNAL OF CELL BIOLOGY
Editorial:
ROCKEFELLER UNIV PRESS
Referencias:
Año: 2019 vol. 218 p. 3883 - 3884
ISSN:
0021-9525
Resumen:
ETAA1 activates the master checkpoint kinase ATR. Bass and Cortez (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201810058) recently reported an intra-mitotic function of ETAA1 that safeguards chromosome stability. In this issue, Achuthankutty et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201905064) describe a mechanism controlling the ATR-activating potential of ETAA1 in S phase to preserve chromosome stability.
