Ability of lipid accumulation product to identify metabolic syndrome in healthy men from Buenos Aires

MARIANA L. TELLECHEA, FLORENCIA ARANGUREN, MARÍA T. MARTÍNEZ-LARRAD, MANUEL SERRANO-RÍOS, MARIANO J. TAVERNA, GUSTAVO D. FRECHTEL. M.J.T. AND G.D.F. CONTRIBUTED EQUALLY TO THIS WORK

DIABETES CARE

AMER DIABETES ASSOC

Año: 2009 vol. 32 p. 85 - 85

0149-5992

The metabolic syndrome is a constellation of cardiovascular and metabolic risk factors associated with insulin resistance, which predisposes individuals to diabetes, and appears to be a multifactorial risk factor for cardiovascular disease, although its clinical significance remains controversial (1). Since it may become useful to be able to predict who will develop metabolic syndrome, we explored the value of lipid accumulation product (LAP), a novel index of central lipid accumulation, which has been associated with cardiovascular disease (2) and diabetes (3). LAP is based on a combination of waist circumference and triglyceride: [LAP = (WC − 65) × TG for men and (WC − 58) × TG for women] (2), where TG is triglyceride and WC is waist circumference. We conducted a cross-sectional population-based survey on metabolic syndrome in Argentinian healthy individuals in order to identify single …