IQUIMEFA   05518
INSTITUTO QUIMICA Y METABOLISMO DEL FARMACO
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Dye-mediated cross linking of Type I collagen hydrogels
Autor/es:
TUTTOLOMONDO MARÍA VICTORIA; VIOSIN HUGO; GALDOPÓRPORA JUAN MANUEL; CORADIN THIBAUD; TRICHET LEA; DESIMONE MARTÍN FEDERICO
Lugar:
CABA
Reunión:
Congreso; VI Congreso SETAC ARG 2016; 2016
Institución organizadora:
SETAC
Resumen:
A large family of azo dyes have been developed and used in the textile industry, including for leather tainting, and are therefore expected to exhibit strong interactions with collagen-based materials. Here we investigate the mechanisms of adsorption of different azo dyes on type I collagen hydrogel. Congo Red (RC), Hydroxynaphtol Blue (AHN) and Bismark Brown (BB) were chosen for the assays. The adsorption process is fast, the adsorbent (collagen) is biodegradable, and azo dyes don´t suffer rupture that could origin products even more toxic than the dye without degradation. The interaction between collagen and dye is chemically-stable limiting the risk of secondary contamination due to dye leaching from the sorbent. Another advantage of such hydrogels is their ability to reduce the generation of waste thanks to their strong reduction in weight and volume upon drying that should reduce the needed storage area leading also to costs reduction. Their application in water remediation would also constitute a new valorization route for industrial processes producing collagen as waste. Type I collagen hydrogels combine low cost, fast sorption, high loading and strong retention capacity together with low storage volume, making them promising materials for dye remediation. Dye-modified hydrogels may also find applications in the biomedical field.