IQUIMEFA   05518
INSTITUTO QUIMICA Y METABOLISMO DEL FARMACO
Unidad Ejecutora - UE
capítulos de libros
Título:
Interaction of Cells with Different Micrometer and Submicrometer Topographies
Autor/es:
MV TUTTOLOMONDO; *MF DESIMONE; PN CATALANO; MG BELLINO
Libro:
Advanced Materials Interfaces
Editorial:
John Wiley & Sons, Inc
Referencias:
Año: 2016; p. 379 - 404
Resumen:
Cell?biomaterial interactions are largely governed by the stiffness and chemical composition of the substrate, although the surface topography has also been shown to play an important role in the adhesion and proliferation of various cell types to different substrates. Actually, the engineering of surfaces to control cell adhesion represents an active area of biomaterials research that aims to meet the requirements of each cell?biomaterial interaction. There are many reported techniques for creating substrates with controlled topography on different materials. Among these, some can be used to create ordered features (e.g. photolithography), while the others are mostly used for creating non-ordered surface patterns (e.g. polymer demixing). We present here what we consider the most relevant methods that were used to generate different micro- and nanotopographical features to study cell?biomaterial interactions.